Simultaneous Determination of Amlodipine, Hydrochlorothiazide, and Valsartan in Pharmaceutical Products by a Combination of Full Spectrum Measurement and Kalman Filter Algorithm

Table 2

Quantification results of AML, HYD, and VAL in a mixture using the Kalman filter with the assumption of initial guesses method (Solution 1).

	Mixture	H1	H2	H3	H4
AML	Co (µg/mL)	0.250	0.500	1.000	5.000
	C (µg/mL)	1.731	0.478	0.530	5.032
	RE (%)	−30.8	−4.5	−47	0.6
HYD	Co (µg/mL)	0.325	0.650	1.300	5.000
	C (µg/mL)	2.794	0.495	1.610	5.910
	RE (%)	−14.0	−23.8	23.85	18.2
VAL	Co (µg/mL)	4.000	8.000	16.000	5.000
	C (µg/mL)	4.796	11.053	29.067	3.949
	RE (%)	19.9	38.2	81.7	−21.03

C_o: concentration in the standard solution; C: calculated concentration.