Simultaneous Determination of Amlodipine, Hydrochlorothiazide, and Valsartan in Pharmaceutical Products by a Combination of Full Spectrum Measurement and Kalman Filter Algorithm

Table 4

Quantification results of AML, HYD, and VAL in a mixture using the Kalman filter with the selection of the approximate initial guesses method.

	Mixture	H1	H2	H3	H4
AML	Co (µg/mL)	0.250	0.500	1.000	5.000
	C (µg/mL)	0.253	0.511	1.016	4.981
	RE (%)	1.2	2.2	1.6	0.4
HYD	Co (µg/mL)	0.325	0.650	1.300	5.000
	C (µg/mL)	0.320	0.646	1.290	5.064
	RE (%)	−1.5	−0.6	−0.8	1.3
VAL	Co (µg/mL)	4.000	8.000	16.000	5.000
	C (µg/mL)	3.99	8.06	16.05	4.821
	RE (%)	−0.2	0.8	0.3	−3.6

C_o: concentration in the standard solution; C: calculated concentration.