Simultaneous Determination of Amlodipine, Hydrochlorothiazide, and Valsartan in Pharmaceutical Products by a Combination of Full Spectrum Measurement and Kalman Filter Algorithm

Table 5

Measured concentrations of AML, HYD, and VAL in the standard mixtures with corresponding RE values.

Mixture	C0,AML (µg/mL)	AML		C0,HYD (µg/mL)	HYD		C0,VAL (µg/mL)	VAL
		CAML (µg/mL)	RE (%)		CHYD (µg/mL)	RE (%)		CVAL (µg/mL)	RE (%)
H1	0.250	0.253	1.2	0.325	0.320	−1.5	4.000	3.990	−0.2
H2	0.500	0.511	2.2	0.650	0.646	−0.6	8.000	8.060	0.8
H3	1.000	1.016	1.6	1.300	1.290	−0.8	16.000	16.050	0.3
H4	5.000	4.981	0.4	5.000	5.064	1.3	5.000	4.8210	−3.6

C_o: concentration in the standard solution; C: calculated concentration; RE: relative error (Section 2.1).