Simultaneous Determination of Amlodipine, Hydrochlorothiazide, and Valsartan in Pharmaceutical Products by a Combination of Full Spectrum Measurement and Kalman Filter Algorithm

Table 8

Method recovery for Exforge HCT tablet samples.

Replicate samples	AML			HYD			VAL
	Cspike (µg/mL)	Cmea (µg/mL)	REV (%)	Cspike (µg/mL)	Cmea (µg/mL)	REV (%)	Cspike (µg/mL)	Cmea (µg/mL)	REV (%)
B1	0	0.965		0	1.168		0	16.997
	0.25	1.200	94.0	0.30	1.451	94.3	4.0	21.112	102.9
	0.50	1.415	90.0	0.60	1.710	90.3	8.0	24.876	98.5
B2	0	0.980		0	1.186		0	17.249
	0.25	1.214	93.6	0.30	1.469	94.3	4.0	21.363	102.9
	0.50	1.450	94.0	0.60	1.753	94.5	8.0	25.497	103.1
B3	0	0.937		0	1.134		0	16.506
	0.25	1.171	93.6	0.30	1.416	94.0	4.0	20.603	102.4
	0.50	1.397	92.0	0.60	1.689	92.5	8.0	24.567	100.8
REVmean (%)	92.9			93.3			101.8