CT-Guided 125I Seed Interstitial Brachytherapy as a Salvage Treatment for Recurrent Spinal Metastases after External Beam Radiotherapy
Table 5
Treatment details of four patients who developed fractures.
Number/gender/age
Diagnosis
Location
Prior therapies (except primary)
time (months)
GTV volume (cc)
Number of seeds/ (Gy)
GTV: (%)
of spinal cord delivered by EBRT/brachytherapy (Gy)
Therapy after seed implant
time (months)
1/M/68
Liver cancer
T11
S + EBRT 40 Gy + CTx
6
61.7
88/141.9
94.8/93.1
25.3/74.1
No
6
2/F/56
Endometrial carcinoma
L4-S1
S + EBRT 50 Gy + CTx
6
61.3 61.3
57/92.2 51/93.5
83.5/81.9 85.8/82.1
38.2/35.6 6.1
No
6
3/F/59
Renal carcinoma
C3-4
S + EBRT 38 Gy
36
24.4
27/102.1
91.7/90.0
35/49.3
No
3
4/F/68
Lung cancer
T7-8
EBRT 40 Gy
10
41.8
45/93.3
89.3/88.1
38.5/46.3
CTx
2
M = male; F = female; S = surgery. time is the time interval between EBRT and 125I seed interstitial brachytherapy. time is calculated from 125I seed implantation performed to fracture developed. Other abbreviations as in Tables 1, 2, and 3.