Clinical Study

CT-Guided 125I Seed Interstitial Brachytherapy as a Salvage Treatment for Recurrent Spinal Metastases after External Beam Radiotherapy

Table 5

Treatment details of four patients who developed fractures.

Number/gender/ageDiagnosisLocationPrior therapies (except primary) time (months)GTV volume (cc)Number of seeds/ (Gy)GTV: (%) of spinal cord delivered by EBRT/brachytherapy (Gy)Therapy after seed implant time (months)

1/M/68Liver cancerT11S + EBRT 40 Gy + CTx661.788/141.994.8/93.125.3/74.1No6
2/F/56Endometrial carcinomaL4-S1S + EBRT 50 Gy + CTx661.3
61.3
57/92.2
51/93.5
83.5/81.9
85.8/82.1
38.2/35.6
6.1
No6
3/F/59Renal carcinomaC3-4S + EBRT 38 Gy3624.427/102.191.7/90.035/49.3No3
4/F/68Lung cancerT7-8EBRT 40 Gy1041.845/93.389.3/88.138.5/46.3CTx2

M = male; F = female; S = surgery.
time is the time interval between EBRT and 125I seed interstitial brachytherapy.
time is calculated from 125I seed implantation performed to fracture developed.
Other abbreviations as in Tables 1, 2, and 3.