BioMed Research International

Prevention and Early Detection of Gastrointestinal Cancers


Publishing date
01 Dec 2019
Status
Closed
Submission deadline
26 Jul 2019

Lead Editor

1Wuhan University, Wuhan, China

2University of Nebraska Medical Center, Omaha, USA

3Huazhong University of Science and Technology, Wuhan, China

4Nanjing Medical University, Nanjing, China

This issue is now closed for submissions.
More articles will be published in the near future.

Prevention and Early Detection of Gastrointestinal Cancers

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Gastrointestinal (GI) cancers, those of the esophagus, stomach, and colon/rectum, are among the most common cancers worldwide. There are more than 4 million new cases each year, which is more than breast and lung cancer cases combined. Despite extensive efforts to improve treatment including the development of new drugs, the prognosis for advanced stages of GI cancers still remains very poor. The early detection of GI cancers before they metastasize to other organs allows definitive local treatment, resulting in excellent survival rates. A defined role for early-detection approaches currently exists in some cancer types, but each approach test has limitations. Primary prevention and early detection have therefore become a major goal of GI cancer research for many years.

The currently available cancer prevention and early-detection approaches have the potential to reduce a large proportion of the cancer burden in the population. However, even if fully implemented, existing methods cannot fully eliminate the cancer burden. Many factors like inflammation, oxidative stress, or nutritional status may play key roles in the pathogenesis of GI cancer. Thus, the aim of this special issue is to identify new preventive and early-detection approaches that exploit the growing knowledge of molecular and biological mechanisms in GI inflammation and cancers. The special issue welcomes basic science and clinical research on early detection or the underlying molecular mechanisms of GI cancer, as well as review articles describing the current state of GI cancer prevention and early detection.

Potential topics include but are not limited to the following:

  • In vivo or in vitro studies related to GI cancers
  • Clinical studies in GI cancers
  • Early detection, biomarker, and diagnosis of GI cancers
  • Oxidative stress, precancerous lesion, or precancerous conditions in the GI tract
  • Preventive strategies such as probiotics, prebiotics, synbiotics, natural products, or new drugs to prevent GI inflammation or cancer

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 2018162
  • - Research Article

ZiYinHuaTan Recipe Inhibits Cell Proliferation and Promotes Apoptosis in Gastric Cancer by Suppressing PI3K/AKT Pathway

Jiahui Yu | Shangjin Song | ... | Xiaoqiang Yue
  • Special Issue
  • - Volume 2020
  • - Article ID 5419634
  • - Research Article

RAS Mutational Status Detection in Tissue, Plasma, and Stool Samples for Colorectal Cancer

Liuying Zhu | Yuanhe Wang | ... | Jingdong Zhang
  • Special Issue
  • - Volume 2020
  • - Article ID 1726309
  • - Review Article

Molecular Aspects of Colorectal Adenomas: The Interplay among Microenvironment, Oxidative Stress, and Predisposition

Gitana Maria Aceto | Teresa Catalano | Maria Cristina Curia
  • Special Issue
  • - Volume 2020
  • - Article ID 9847591
  • - Clinical Study

Quantitative Diagnosis of Atrophic Gastritis by Probe-Based Confocal Laser Endomicroscopy

Xiaoyun Yu | Jie Chen | ... | Xiaohua Hou
  • Special Issue
  • - Volume 2020
  • - Article ID 7243029
  • - Research Article

Precancerous Gastric Lesions with Helicobacter pylori vacA+/babA2+/oipA+ Genotype Increase the Risk of Gastric Cancer

Theeraya Simawaranon Bartpho | Wareeporn Wattanawongdon | ... | Chavaboon Dechsukhum
  • Special Issue
  • - Volume 2020
  • - Article ID 7828392
  • - Research Article

Study of the Relationship between Microbiome and Colorectal Cancer Susceptibility Using 16SrRNA Sequencing

Wanxin Liu | Ren Zhang | ... | Qingming Wu
  • Special Issue
  • - Volume 2020
  • - Article ID 5958272
  • - Research Article

Hypoxia Induces Growth Differentiation Factor 15 to Promote the Metastasis of Colorectal Cancer via PERK-eIF2α Signaling

Hongtu Zheng | Yuchen Wu | ... | Sanjun Cai
  • Special Issue
  • - Volume 2019
  • - Article ID 6831520
  • - Review Article

Preventive and Therapeutic Roles of Berberine in Gastrointestinal Cancers

Siwang Hu | Ruochi Zhao | ... | Shuangshuang Wang
  • Special Issue
  • - Volume 2019
  • - Article ID 2615921
  • - Research Article

Integrated Bioinformatics Analysis Identifies Hub Genes Associated with the Pathogenesis and Prognosis of Esophageal Squamous Cell Carcinoma

Hui Zhang | Jianing Zhong | ... | Jincai Zhong
  • Special Issue
  • - Volume 2019
  • - Article ID 5953036
  • - Review Article

Circulating Tumour Cells, Circulating Tumour DNA and Circulating Tumour miRNA in Blood Assays in the Different Steps of Colorectal Cancer Management, a Review of the Evidence in 2019

Niki Christou | Jeremy Meyer | ... | Muriel Mathonnet
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision67 days
Acceptance to publication31 days
CiteScore3.600
Impact Factor2.276
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