BioMed Research International

Molecular Biomarkers: Tools of Medicine


Publishing date
15 Nov 2013
Status
Published
Submission deadline
28 Jun 2013

1Edward Waters College, 1658 Kings Road, Jacksonville, FL 32209, USA

2Department of Biological Sciences, Alabama State University, Room no. 325, Life Science Building, 1627 Hall Street, Montgomery, AL 36104, USA

3College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, 1520 M L King Boulevard, Tallahassee, FL 32307, USA

4Laboratory of General Physiology, Department of Biological and Environmental Sciences and Technologies, University of Salento, Via Provinciale Lecce-Monteroni, 73100 Lecce, Italy

5Department of Translational Science and Molecular Medicine, MSU College of Human Medicine and Van Andel Institute, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA


Molecular Biomarkers: Tools of Medicine

Description

In medicine, a biomarker can be a substance that is introduced into an organism as a means to examine organ function. It can also be a substance whose detection indicates a particular disease state. More specifically, a biomarker indicates a change in expression or state of a protein that correlates with the risk or progression of a disease. There has been an explosion in the discovery of biomarkers for diagnosis, disease monitoring, and prognostic evaluation. Molecular biomarkers are emerging as the key indices for the management of patients with significant diseases. Motivated by the systematic effort to define the human genome, the creation of rapid analytic technologies for evaluating nucleic acids and proteins has provided the technological “boom ” for the development of “molecular biomarkers.” Collaboration and cooperation between stakeholders involved in biomarker development, application, and regulation may be the most expeditious route toward the translation of laboratory discovery into patient management.

The main focus of this special issue will be on the advances in our understanding of how biological processes interact, thus enabling such technologies as genomics, proteomics, metabolomics, and lipidomics-combined with drug discovery and development, high-throughput screening, and in silico drug development, place science on the threshold of innovative management. This special issue will become an international forum for researchers to summarize the most recent developments and ideas in the field, with a special emphasis given to the expeditious path toward the translation of laboratory discovery into patient management within the last five years. Potential topics include, but are not limited to:

  • Identification of biomarkers
  • Disease-related biomarkers
  • Drug-related biomarkers
  • Biomarkers in drug development
  • Technological advances
  • Discovery of molecular biomarkers and elucidation of their role
  • Imaging biomarkers and potential disadvantages
  • Formalization and approval of their application in modern medicine

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/biotechnology/mbtm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 595496
  • - Editorial

Molecular Biomarkers: Tools of Medicine

Prabir K. Mandal | Shivani Soni | ... | Sudhish Mishra
  • Special Issue
  • - Volume 2013
  • - Article ID 295635
  • - Research Article

Defects in Base Excision Repair Sensitize Cells to Manganese in S. cerevisiae

Adrienne P. Stephenson | Tryphon K. Mazu | ... | Hernan Flores-Rozas
  • Special Issue
  • - Volume 2013
  • - Article ID 891391
  • - Research Article

Practical Guidance for Implementing Predictive Biomarkers into Early Phase Clinical Studies

Matthew J. Marton | Russell Weiner
  • Special Issue
  • - Volume 2013
  • - Article ID 241780
  • - Research Article

Circulating microRNAs and Kallikreins before and after Radical Prostatectomy: Are They Really Prostate Cancer Markers?

Maria Giulia Egidi | Giovanni Cochetti | ... | Ettore Mearini
  • Special Issue
  • - Volume 2013
  • - Article ID 563751
  • - Research Article

A Novel Differential Predict Model Based on Matrix-Assisted Laser Ionization Time-of-Flight Mass Spectrometry and Serum Ferritin for Acute Graft-versus-Host Disease

Chun-yan Zhang | Shu-hong Wang | ... | Ya-Ping Tian
  • Special Issue
  • - Volume 2013
  • - Article ID 798054
  • - Research Article

The use of Multidimensional Data to Identify the Molecular Biomarker for Pancreatic Ductal Adenocarcinoma

Liwei Zhuang | Yue Qi | ... | Yili Fu
  • Special Issue
  • - Volume 2013
  • - Article ID 195692
  • - Research Article

Clinical Evaluation and Cost-Effectiveness Analysis of Serum Tumor Markers in Lung Cancer

Rong Wang | Guoqing Wang | ... | Yunde Liu
  • Special Issue
  • - Volume 2013
  • - Article ID 107940
  • - Research Article

Immune Parameters in The Prognosis and Therapy Monitoring of Cutaneous Melanoma Patients: Experience, Role, and Limitations

Monica Neagu | Carolina Constantin | Sabina Zurac
  • Special Issue
  • - Volume 2013
  • - Article ID 354582
  • - Research Article

Comparative Gene Expression Profiling in Human Cumulus Cells according to Ovarian Gonadotropin Treatments

Said Assou | Delphine Haouzi | ... | Samir Hamamah
  • Special Issue
  • - Volume 2013
  • - Article ID 731516
  • - Review Article

Aptamers: Novel Molecules as Diagnostic Markers in Bacterial and Viral Infections?

Flávia M. Zimbres | Attila Tárnok | ... | Carsten Wrenger
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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