BioMed Research International

Angiogenesis and Vasculogenesis in Health and Disease


Status
Published

1Catholic University of the Sacred Heart, Rome, Italy

2University of Pavia, Pavia, Italy

3Yale University School of Medicine, New Haven, USA

4IRCCS – G. B. Bietti Foundation, Rome, Italy

5Boston University Henry M. Goldman School of Dental Medicine, Boston, USA


Angiogenesis and Vasculogenesis in Health and Disease

Description

The first scientific evidence of angiogenesis dates back to the late 1700s when the Scottish surgeon John Hunter suggested that the balance between vascularity and metabolic requirements occurs in both health and disease. Vasculogenesis and angiogenesis occur during the growth of new blood vessels. Specifically, vasculogenesis refers to the differentiation of precursor cells or angioblasts into endothelial cells and the de novo formation of a primitive vascular network, whereas angiogenesis occurs when new capillaries grow from preexisting blood vessels. At the embryonic level, blood vessels can form through both mechanisms. The modern history of angiogenesis began more than 30 years ago when Judah Folkman hypothesized and reported that tumor growth is angiogenesis-dependent, turning the study of this process into one of the most exciting areas in modern biomedical research. It has been widely accepted that abnormal angiogenesis represents an important process in many pathological conditions, as well documented by the ever growing number of publications in this field during the last two decades. We invite investigators to contribute original research articles as well as review articles that will help in understanding the mechanisms of angiogenesis and vasculogenesis in health and disease, signaling pathways in vascular cells, and the development of novel therapies to treat angiogenesis-related diseases. Both experimental and theoretical papers are welcome.

Potential topics include, but are not limited to:

  • Mechanisms of blood vessel formation
  • Vessel structure, integrity, and permeability
  • Signaling pathways and Ca2+ dynamics in vascular cells
  • Redox signaling in angiogenesis
  • Tumor angiogenesis and antiangiogenic drug resistance
  • Angiogenesis in ischemic diseases
  • Angiogenesis in acute and chronic inflammation
  • Endothelial progenitor cells in health and disease
  • Angiogenesis-based medicine

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 126582
  • - Editorial

Angiogenesis and Vasculogenesis in Health and Disease

Alessio D’Alessio | Francesco Moccia | ... | Themis R. Kyriakides
  • Special Issue
  • - Volume 2015
  • - Article ID 747864
  • - Research Article

Isolation and Characterization of Human Lung Lymphatic Endothelial Cells

Bruno Lorusso | Angela Falco | ... | Federico Quaini
  • Special Issue
  • - Volume 2015
  • - Article ID 652474
  • - Research Article

Production of Human Endothelial Cells Free from Soluble Xenogeneic Antigens for Bioartificial Small Diameter Vascular Graft Endothelization

Juliana Lott de Carvalho | Alessandra Zonari | ... | Alfredo Miranda Goes
  • Special Issue
  • - Volume 2015
  • - Article ID 965271
  • - Research Article

Regulation of Angiogenic Functions by Angiopoietins through Calcium-Dependent Signaling Pathways

Irene Pafumi | Annarita Favia | ... | Antonio Filippini
  • Special Issue
  • - Volume 2015
  • - Article ID 742646
  • - Research Article

Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension

Lidia Gackowska | Mieczyslaw Litwin | ... | Jacek Michalkiewicz
  • Special Issue
  • - Volume 2015
  • - Article ID 317905
  • - Research Article

OSM Enhances Angiogenesis and Improves Cardiac Function after Myocardial Infarction

Xiaotian Zhang | Di Zhu | ... | Dongdong Sun
  • Special Issue
  • - Volume 2015
  • - Article ID 968927
  • - Research Article

Epoetin Alpha and Epoetin Zeta: A Comparative Study on Stimulation of Angiogenesis and Wound Repair in an Experimental Model of Burn Injury

Natasha Irrera | Alessandra Bitto | ... | Domenica Altavilla
  • Special Issue
  • - Volume 2015
  • - Article ID 549412
  • - Review Article

Hypoxia-Inducible Factor-1 in Physiological and Pathophysiological Angiogenesis: Applications and Therapies

Agnieszka Zimna | Maciej Kurpisz
  • Special Issue
  • - Volume 2015
  • - Article ID 719316
  • - Research Article

Activation of Cell Surface Bound 20S Proteasome Inhibits Vascular Cell Growth and Arteriogenesis

Wulf D. Ito | Natalie Lund | ... | Thomas Meinertz
  • Special Issue
  • - Volume 2015
  • - Article ID 142359
  • - Review Article

The Role of Mast Cell Specific Chymases and Tryptases in Tumor Angiogenesis

Devandir Antonio de Souza Junior | Ana Carolina Santana | ... | Maria Celia Jamur
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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