BioMed Research International

Preventing Hearing Loss and Restoring Hearing: A New Outlook


Status
Published

1Department of Physiology and Centre for Brain Research, The University of Auckland, Private Bag 92019, Auckland, New Zealand

2Department of Physiology, Section of Audiology and Centre for Brain Research, The University of Auckland, Private Bag 92019, Auckland, New Zealand

3Department of Physiology, Monash University, Melbourne, VIC 3800, Australia

4UCL Ear Institute, University College London, London WC1X8EE, UK


Preventing Hearing Loss and Restoring Hearing: A New Outlook

Description

People with hearing loss represent one of the largest disability groups worldwide, and the prevalence of hearing loss is predicted to rise with an ageing population. Substantial progress has been made in recent years towards understanding some of the biological processes involved in the development of hearing impairment as well as therapeutic ways to prevent and mitigate the hearing loss. For example, we have better understanding of the maintenance and regeneration of the sensorineural tissues in the cochlea. The sensory hair cells in the cochlea can potentially be regenerated by reactivating genes that control their development, and various types of stem cells can be transformed into sensory hair cells or auditory neurones. In addition, drugs that reduce oxidative stress or prevent apoptosis have been shown to protect hearing from excessive noise and ototoxic drugs. Furthermore, our knowledge of central auditory changes associated with the peripheral injury or auditory processing problems is rapidly increasing. The aim of this special issue is to advance our understanding of the causes and mechanisms of hearing loss, reactive auditory plasticity, and rehabilitation from hearing loss and propose novel strategies to protect and restore hearing.

We invite investigators to contribute original research articles and review articles that will address the causes and mechanisms of hearing loss, changes in central auditory pathways after cochlear injury or congenital deafness, diagnostic evaluation and prevention of hearing loss, rehabilitation after hearing loss, and biological restoration of hearing. Potential topics include, but are not limited to:

Potential topics include, but are not limited to:

  • Molecular and cellular mechanisms underlying sensorineural hearing loss
  • Animal models of presbyacusis and noise-induced and drug-induced hearing loss
  • Genetic models of deafness
  • Auditory plasticity and rehabilitation after hearing loss
  • The link between hearing loss and tinnitus
  • Latest technologies for clinical evaluation of hearing loss
  • Prevention of hearing loss
  • New pathways for hair cell regeneration
  • Cell-, drug-, and gene-based therapies to restore hearing

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 868716
  • - Editorial

Preventing Hearing Loss and Restoring Hearing: A New Outlook

Srdjan M. Vlajkovic | Peter R. Thorne | ... | Jonathan E. Gale
  • Special Issue
  • - Volume 2015
  • - Article ID 617207
  • - Review Article

Reactive Oxygen Species, Apoptosis, and Mitochondrial Dysfunction in Hearing Loss

Teru Kamogashira | Chisato Fujimoto | Tatsuya Yamasoba
  • Special Issue
  • - Volume 2014
  • - Article ID 350504
  • - Review Article

Electroacoustic Stimulation: Now and into the Future

S. Irving | L. Gillespie | ... | A. K. Wise
  • Special Issue
  • - Volume 2014
  • - Article ID 652838
  • - Research Article

Development of a Test of Suprathreshold Acuity in Noise in Brazilian Portuguese: A New Method for Hearing Screening and Surveillance

Nara Vaez | Liliane Desgualdo-Pereira | Alessia Paglialonga
  • Special Issue
  • - Volume 2014
  • - Article ID 356415
  • - Research Article

BDNF Increases Survival and Neuronal Differentiation of Human Neural Precursor Cells Cotransplanted with a Nanofiber Gel to the Auditory Nerve in a Rat Model of Neuronal Damage

Yu Jiao | Björn Palmgren | ... | Petri Olivius
  • Special Issue
  • - Volume 2014
  • - Article ID 841489
  • - Research Article

Adenosine Amine Congener as a Cochlear Rescue Agent

Srdjan M. Vlajkovic | Hao Chang | ... | Peter R. Thorne
  • Special Issue
  • - Volume 2014
  • - Article ID 367939
  • - Review Article

Kölliker’s Organ and the Development of Spontaneous Activity in the Auditory System: Implications for Hearing Dysfunction

M. W. Nishani Dayaratne | Srdjan M. Vlajkovic | ... | Peter R. Thorne
  • Special Issue
  • - Volume 2014
  • - Article ID 198153
  • - Research Article

Cortical Electrophysiological Markers of Language Abilities in Children with Hearing Aids: A Pilot Study

David Bakhos | Hélène Delage | ... | Nicole Bruneau
  • Special Issue
  • - Volume 2014
  • - Article ID 724195
  • - Research Article

The Effects of Acute Stress-Induced Sleep Disturbance on Acoustic Trauma-Induced Tinnitus in Rats

Yiwen Zheng | Lucy Stiles | ... | Paul F. Smith
  • Special Issue
  • - Volume 2014
  • - Article ID 925485
  • - Review Article

Prevention and Restoration of Hearing Loss Associated with the Use of Cisplatin

Felician Chirtes | Silviu Albu
BioMed Research International
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Acceptance rate31%
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CiteScore3.600
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