BioMed Research International

Plasma Cell Neoplasms: Genetics, Pathobiology, and New Therapeutic Strategies


Publishing date
15 Aug 2014
Status
Published
Submission deadline
28 Mar 2014

Lead Editor

1Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul 110-744, Republic of Korea

2Nagoya City Higashi General Hospital, Wakamizu, Chikusa-Ku, Nagoya, Japan

3Cancer Science Institute of Singapore, NUS, Singapore


Plasma Cell Neoplasms: Genetics, Pathobiology, and New Therapeutic Strategies

Description

Plasma cell neoplasms are a phenotypically heterogeneous disorder with broad spectrum, including plasma cell myeloma, monoclonal gammopathy of unknown significance, and amyloidosis. Each plasma cell neoplasm is defined by diagnostic criteria, and accordingly therapeutic strategies are developed. Scientists often have a difficulty in discovering genetics of plasma cell neoplasms due to the sorting problem. Deep sequencing utilizing next generation sequencing or single cell genomics is expected to break through this barrier.

Since the introduction of bortezomib, novel therapeutic agents have led to the improvement of survival and novel tools to characterize the plasma cell neoplasms that provide better care to patients.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular pathology underlying plasma cell neoplasms, the design of strategies to treat these conditions, and the evaluation of outcomes. We are particularly interested in articles describing the changes in epidemiology, pathobiology of signal pathways, measuring outcomes from treatment trials, advances in molecular genetics and molecular diagnostics, new insights into plasma cell neoplasms using single cell genomics, siRNA, stem cell transplantation, and cytogenetics. Potential topics include, but are not limited to:

  • Genetic changes of plasma cell myeloma discovered by next generation sequencing
  • Epidemiology of plasma cell myeloma
  • New technics for plasma cell sorting
  • Cytogenetic changes that distinguish each plasma cell neoplasm
  • New therapeutic strategy for plasma cell myeloma
  • New parameters in accessing treatment response
  • Ethnic differences in the genetic changes of plasma cell neoplasms
  • Epidemiology of AL amyloidosis
  • New therapeutic trials for amyloidosis
  • Changing trends in epidemiology of monoclonal gammopathy of unknown significance
  • Therapeutic strategy for monoclonal gammopathy of unknown significance
  • Predictive factors for progression of MGUS to myeloma

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/hematology/plasm/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 513170
  • - Research Article

Plasma Levels of Osteopontin and Vascular Endothelial Growth Factor in Association with Clinical Features and Parameters of Tumor Burden in Patients with Multiple Myeloma

Toni Valković | Emina Babarović | ... | Nives Jonjić
  • Special Issue
  • - Volume 2014
  • - Article ID 521586
  • - Review Article

MicroRNA: Important Player in the Pathobiology of Multiple Myeloma

Chonglei Bi | Wee Joo Chng
  • Special Issue
  • - Volume 2014
  • - Article ID 209670
  • - Research Article

Genome-Wide Screening of Cytogenetic Abnormalities in Multiple Myeloma Patients Using Array-CGH Technique: A Czech Multicenter Experience

Jan Smetana | Jan Frohlich | ... | Petr Kuglik
  • Special Issue
  • - Volume 2014
  • - Article ID 647238
  • - Research Article

Clinical Comparisons of Two Free Light Chain Assays to Immunofixation Electrophoresis for Detecting Monoclonal Gammopathy

Han-Sung Kim | Hyun Soo Kim | ... | Min-Jeong Park
  • Special Issue
  • - Volume 2014
  • - Article ID 145619
  • - Research Article

Elevated Red Blood Cell Distribution Width as a Simple Prognostic Factor in Patients with Symptomatic Multiple Myeloma

Hyewon Lee | Sun-Young Kong | ... | Hyeon-Seok Eom
  • Special Issue
  • - Volume 2014
  • - Article ID 804182
  • - Research Article

Serum Parathyroid Hormone Is a New Potential Risk Factor in Multiple Myeloma

Min-Gu Kang | Eun-Jeong Won | ... | Myung-Geun Shin
  • Special Issue
  • - Volume 2014
  • - Article ID 456037
  • - Review Article

Salvage Therapy of Multiple Myeloma: The New Generation Drugs

Alessandra Romano | Concetta Conticello | ... | Francesco Di Raimondo
  • Special Issue
  • - Volume 2014
  • - Article ID 363540
  • - Research Article

MYD88 L265P Mutations Are Correlated with 6q Deletion in Korean Patients with Waldenström Macroglobulinemia

Jung-Ah Kim | Kyongok Im | ... | Seon Young Kim
  • Special Issue
  • - Volume 2014
  • - Article ID 982504
  • - Research Article

Bone Marrow Plasma Cell Assessment before Peripheral Blood Stem Cell Mobilization in Patients with Multiple Myeloma Undergoing Autologous Stem Cell Transplantation

Sung-Eun Lee | Jae-Ho Yoon | ... | Chang-Ki Min
  • Special Issue
  • - Volume 2014
  • - Article ID 413149
  • - Research Article

The Impact of Hyperglycemia on Risk of Severe Infections during Early Period of Induction Therapy in Patients with Newly Diagnosed Multiple Myeloma

Sung-Hoon Jung | Hee-Chang Jang | ... | Je-Jung Lee
BioMed Research International
 Journal metrics
See full report
Acceptance rate8%
Submission to final decision110 days
Acceptance to publication24 days
CiteScore5.300
Journal Citation Indicator-
Impact Factor-
 Submit Evaluate your manuscript with the free Manuscript Language Checker

We have begun to integrate the 200+ Hindawi journals into Wiley’s journal portfolio. You can find out more about how this benefits our journal communities on our FAQ.