BioMed Research International

The Epithelium–Molecular Landscaping for an Interactive Barrier


Publishing date
01 Jan 2010
Status
Published
Submission deadline
01 Jul 2009

Lead Editor

1Department of Molecular Biology and Microbiology, School of Medicine, University of Central Florida College of Medicine, Orlando, FL 32816, USA

2Department of Nephrology, Kumamoto University Graduate School of Medical Sciences, Kumamoto 860-8556, Japan

3UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin 4, Ireland

4Departments of Urology and Pathology, NYU Langone Medical Center, New York, NY 10016, USA


The Epithelium–Molecular Landscaping for an Interactive Barrier

Description

The epithelium is the most unique structure of the body as it is the layer that faces the outside environment. The epithelium must protect the body from the various environmental insults, such as pathogens, particles, and mechanical forces. In this role, the epithelium will sustain injuries, which must then be properly repaired to restore the original tissue structure and integrity. The epithelium must at the same time allow material transfer and exchange with the outside environment, absorbing nutrients, and removing waste. At the plasma membrane of the epithelial cells, these tasks are carried out by structural proteins and protein complexes, receptors, channels, carriers and pumps, and proteases. These molecules must be delivered to the appropriate topological location, while the abundance and activities of these molecules must also be precisely regulated. The goal of this special issue is to develop a comprehensive picture of the epithelial membrane molecular landscape in multiple dimensions: transport and trafficking, changes during normal tissue development and differentiation, changes during tissue injury, and changes during tissue repair and regeneration.

We are inviting original research and review articles addressing the epithelial membrane molecular landscape with a functional interpretation on the dynamic roles played by the epithelium. The topics to be considered include, but are not limited to:

  • Intercellular adhesions and junctions
  • Channels, carriers, and pumps
  • Membrane-anchored receptors
  • Membrane-anchored proteases
  • Endocytosis, recycling of membrane proteins, and transcytosis
  • Invasion of pathogens
  • Mechanosensing
  • Epithelial-matrix adhesions

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/jbb/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2010
  • - Article ID 870506
  • - Editorial

The Epithelium—Molecular Landscaping for an Interactive Barrier

Karl Chai | Kenichiro Kitamura | ... | Xue-Ru Wu
  • Special Issue
  • - Volume 2010
  • - Article ID 103976
  • - Research Article

Impact of Lentiviral Vector-Mediated Transduction on the Tightness of a Polarized Model of Airway Epithelium and Effect of Cationic Polymer Polyethylenimine

Stefano Castellani | Sante Di Gioia | ... | Massimo Conese
  • Special Issue
  • - Volume 2010
  • - Article ID 956897
  • - Review Article

Claudin 1 in Breast Tumorigenesis: Revelation of a Possible Novel “Claudin High” Subset of Breast Cancers

Yvonne Myal | Etienne Leygue | Anne A. Blanchard
  • Special Issue
  • - Volume 2010
  • - Article ID 307231
  • - Research Article

TNF 𝛼 Induces Choroid Plexus Epithelial Cell Barrier Alterations by Apoptotic and Nonapoptotic Mechanisms

Christian Schwerk | Kasia Rybarczyk | ... | Tobias Tenenbaum
  • Special Issue
  • - Volume 2010
  • - Article ID 805405
  • - Research Article

Gelsolin Restores A -Induced Alterations in Choroid Plexus Epithelium

Teo Vargas | Desiree Antequera | ... | Eva Carro
  • Special Issue
  • - Volume 2010
  • - Article ID 940741
  • - Review Article

The Chick Chorioallantoic Membrane: A Model of Molecular, Structural, and Functional Adaptation to Transepithelial Ion Transport and Barrier Function during Embryonic Development

Maria Gabriella Gabrielli | Daniela Accili
  • Special Issue
  • - Volume 2010
  • - Article ID 394198
  • - Research Article

Volume Density, Distribution, and Ultrastructure of Secretory and Basolateral Membranes and Mitochondria Predict Parietal Cell Secretory (Dys)function

Marian L. Miller | Anastasia Andringa | ... | Gary E. Shull
  • Special Issue
  • - Volume 2010
  • - Article ID 525180
  • - Research Article

Regulation of P-Glycoprotein in Renal Proximal Tubule Epithelial Cells by LPS and TNF-α

Suzanne Heemskerk | Janny G. P. Peters | ... | Rosalinde Masereeuw
  • Special Issue
  • - Volume 2010
  • - Article ID 402593
  • - Review Article

The Dual Role of Zonula Occludens (ZO) Proteins

H. Bauer | J. Zweimueller-Mayer | ... | H. C. Bauer
  • Special Issue
  • - Volume 2010
  • - Article ID 289360
  • - Research Article

Neutrophils Compromise Retinal Pigment Epithelial Barrier Integrity

Jiehao Zhou | Shikun He | ... | David R. Hinton
BioMed Research International
 Journal metrics
Acceptance rate30%
Submission to final decision67 days
Acceptance to publication32 days
CiteScore3.600
Impact Factor2.276
 Submit

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.