BioMed Research International

Modulation of Lung Immune Response


Publishing date
20 Sep 2013
Status
Published
Submission deadline
03 May 2013

1Universidade Federal do Triângulo Mineiro, 38025-180, Uberaba, MG, Brazil

2Federal University of Santa Catarina and Reference Centers for Innovative Technologies Foundation (CERTI), 88040-970 Florianopolis, SC, Brazil

3University of California, Berkeley, CA 94720, USA


Modulation of Lung Immune Response

Description

In recent decades, considerable progress has been made in the understanding of genetic and immunological factors that contribute to the development and/or treatment of airway disorders. The use of molecular and cellular assays together with knockout animals has contributed significantly to this evolution. Despite this, however, the current therapy for the treatment of airway disorders has not changed to the same degree and is still far from ideal.

In an attempt to respond to this need, one of the areas that have been highlighted most recently is immunology. Knowledge of the participation of the innate and adaptive immune response on the pathophysiological process of infectious and noninfectious airway injuries is rapidly expanding and the advances in the fields of biomedicine and biotechnology have been decisive to this expansion. The innate and adaptive immune system, as well as structural cells, modulates the quantity and quality of airway inflammatory response. Aberrant immune responses, including those induced for allergens, environmental pollutants, infectious agents, acids, and others, promote excessive leukocyte recruitment, production of proinflammatory cytokines, chemokines, and other immunomodulator mediators which are critical to initiate and maintain airway disorders. So, we take a particular interest in manuscripts on the relevance of structural cells, innate and adaptive host responses on modulation/induction, repair, or therapy in the airways. Reviews and original papers that demonstrate the results of clinical, preclinical, or experimental studies of cytokines, antibodies, peptides, RNA interference (RNAi), substances from plants, or other origins that modify immune response for therapeutic purposes are also welcome. In addition, once nanotechnology has a profound impact in many scientific fields and an exponential growth, the impact of colloidal drug delivery systems as carriers for bioactive agents (active substances) in the airways will be interesting. Moreover, papers dealing with detection methods of innate immune parameters in the airways as well as the demonstration of new models to analyze airway disorders would be also interesting. Potential topics include, but are not limited to:

  • The role of innate and adaptive immune system and structural cells on airway disorders
  • The role of cytokines, chemokines, and lipid mediators on airway disorders
  • Infectious lung diseases
  • Modulation of airway inflammation
  • Preclinical and clinical studies of acute and chronic lung inflammation
  • Preclinical and clinical assays evaluating compounds or mediators with the potential to be used in the treatment of airway disorders
  • Identification of natural or synthetic bioactive molecules with potential to be used in the treatment of airway disorders

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/immunology/mlir/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 239020
  • - Editorial

Modulation of Lung Immune Response

Alexandre de Paula Rogerio | Carlo José Freire Oliveira | ... | Oliver Haworth
  • Special Issue
  • - Volume 2013
  • - Article ID 151807
  • - Research Article

Perinatal Exposure to Insecticide Methamidophos Suppressed Production of Proinflammatory Cytokines Responding to Virus Infection in Lung Tissues in Mice

Wataru Watanabe | Hiroki Yoshida | ... | Masahiko Kurokawa
  • Special Issue
  • - Volume 2013
  • - Article ID 109219
  • - Clinical Study

Prevalence of Bronchiectasis in Asthma according to Oral Steroid Requirement: Influence of Immunoglobulin Levels

Manel Luján | Xavier Gallardo | ... | Christian Domingo
  • Special Issue
  • - Volume 2013
  • - Article ID 742184
  • - Research Article

Low pH Environmental Stress Inhibits LPS and LTA-Stimulated Proinflammatory Cytokine Production in Rat Alveolar Macrophages

Stanley F. Fernandez | Christopher Fung | ... | Paul R. Knight
  • Special Issue
  • - Volume 2013
  • - Article ID 576479
  • - Review Article

Potential Effects of Medicinal Plants and Secondary Metabolites on Acute Lung Injury

Daniely Cornélio Favarin | Jhony Robison de Oliveira | ... | Alexandre de Paula Rogerio
  • Special Issue
  • - Volume 2013
  • - Article ID 759760
  • - Review Article

The Multifaceted Aspects of Interstitial Lung Disease in Rheumatoid Arthritis

Lorenzo Cavagna | Sara Monti | ... | Roberto Caporali
  • Special Issue
  • - Volume 2013
  • - Article ID 474132
  • - Research Article

Modulation of the Effects of Lung Immune Response on Bone Marrow by Oral Antigen Exposure

P. Xavier-Elsas | C. L. C. A. Silva | ... | M. I. Gaspar-Elsas
  • Special Issue
  • - Volume 2013
  • - Article ID 523761
  • - Research Article

Antileukotriene Reverts the Early Effects of Inflammatory Response of Distal Parenchyma in Experimental Chronic Allergic Inflammation

Nathália Brandão Gobbato | Flávia Castro Ribas de Souza | ... | Edna Aparecida Leick
  • Special Issue
  • - Volume 2013
  • - Article ID 560141
  • - Research Article

Intracellular Secretory Leukoprotease Inhibitor Modulates Inositol 1,4,5-Triphosphate Generation and Exerts an Anti-Inflammatory Effect on Neutrophils of Individuals with Cystic Fibrosis and Chronic Obstructive Pulmonary Disease

Emer P. Reeves | Nessa Banville | ... | Noel G. McElvaney
  • Special Issue
  • - Volume 2013
  • - Article ID 759361
  • - Research Article

The SDF-1α3 A Genetic Variation Is Correlated with Susceptibility of Asthma in Iranian Patients

Houshang Rafatpanah | Masoud Amin | ... | Jamile Samadi
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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