BioMed Research International

Molecular Diagnostics

Publishing date
19 Apr 2013
Submission deadline
30 Nov 2012

Lead Editor

1Center for Genetic Medicine Research, Children's National Medical Center, 111 Michigan Avenue, NW, Washington, DC 20010, USA

2Centre for DNA Fingerprinting and Diagnostics, 4-1-714, Tuljaguda Complex, Mozamzahi Road, Nampally, Hyderabad 500001, India

3National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411 007, India

Molecular Diagnostics


Molecular diagnostics dates back to the 1980s but has seen exponential growth since the turn of the century. The field has a wide range of applications, including identifying individuals at risk for developing certain conditions (either genetic or nongenetic), screening apparently healthy populations, determining prognosis (as with cancer), monitoring patients' response to therapy, and diagnosing disease. Molecular diagnosis is very helpful tool for the families with the heritable conditions, as with its help it is very easy and accurate to provide the carrier prenatal counseling to the family member at risk. Next-generation sequencing (NGS) applications have a tremendous impact on molecular diagnostic/medicine and have taken the field of molecular diagnosis to the new heights.

The main focus of this special issue will be on the new and existing molecular diagnostics techniques available for the diagnosis of heritable, nonheritable, and infectious conditions. We also want to focus on how the use of current techniques can help the laboratory to better serve the patients population in the coming years. The special issue will become an international forum for researchers to summarize the most recent developments and ideas in the field, with a special emphasis given to the technical and observational results obtained within the last five years. Potential topics include, but are not limited to:

  • Next-generation sequencing technology (Exome and targeted)
  • Real-time analysis pipeline
  • Copy number variants
  • Fluorescent in situ hybridization
  • Comparative genomic hybridization techniques (array)
  • RNA-based diagnosis (microarray)
  • Mass spectrometric techniques
  • Managing and reporting the variant to the patients (genetic counseling)
  • Direct consumer testing
  • Global networks of sharing the data
  • New hardware and software development
  • Future strategies

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:


  • Special Issue
  • - Volume 2013
  • - Article ID 387486
  • - Editorial

Molecular Diagnostics

Akanchha Kesari | Ashwin Dalal | ... | Sachchida Nand Pandey
  • Special Issue
  • - Volume 2013
  • - Article ID 648420
  • - Research Article

PSCA and Oct-4 Expression in the Benign and Malignant Lesions of Gallbladder: Implication for Carcinogenesis, Progression, and Prognosis of Gallbladder Adenocarcinoma

Qiong Zou | Leping Yang | ... | Xi Fu
  • Special Issue
  • - Volume 2013
  • - Article ID 465179
  • - Research Article

Molecular Characterization and Clinical Impact of TMPRSS2-ERG Rearrangement on Prostate Cancer: Comparison between FISH and RT-PCR

A. Fernández-Serra | L. Rubio | ... | J. A. López-Guerrero
  • Special Issue
  • - Volume 2013
  • - Article ID 783131
  • - Review Article

Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture

Debasish Paul | Avinash Kumar | ... | Rapole Srikanth
  • Special Issue
  • - Volume 2013
  • - Article ID 793502
  • - Research Article

Detection of Intracellular Factor VIII Protein in Peripheral Blood Mononuclear Cells by Flow Cytometry

Gouri Shankar Pandey | Sandra C. Tseng | ... | Zuben E. Sauna
  • Special Issue
  • - Volume 2013
  • - Article ID 746053
  • - Research Article

Prescription Surveillance and Polymerase Chain Reaction Testing to Identify Pathogens during Outbreaks of Infection

Hiroaki Sugiura | Tsuguto Fujimoto | ... | Yasushi Ohkusa
  • Special Issue
  • - Volume 2013
  • - Article ID 757490
  • - Research Article

Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods

Katja Tuononen | Virinder Kaur Sarhadi | ... | Sakari Knuutila
BioMed Research International
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Acceptance to publication22 days
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