BioMed Research International

Endothelium in Diseased States


Publishing date
04 Apr 2014
Status
Published
Submission deadline
15 Nov 2013

Lead Editor

1Laboratory of Neurohumoral Regulation of Haemodynamics, Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Sienkiewiczova 1, 813 71 Bratislava, Slovak Republic

2LUNAM Université, INSERM UMR U1063, Université d’Angers IBS-IRIS, Rue des Capucins, Angers, France

3Department of Physiology, Faculty of Medicine, Universidad Autónoma de Madrid, Arzobispo Morcillo 4, 280 29 Madrid, Spain

4Department of Biomedicine, Aarhus University, Ole Worms Alle 4, Bygning 1163, 8000 Aarhus, Denmark


Endothelium in Diseased States

Description

Endothelium is the largest endocrine organ which is essential for maintenance of homeostasis of the entire body. Endothelium operates by a broad spectrum of signaling molecules controlling the contractile state of vascular smooth muscles; long distance intercellular synchronization within the vascular wall; adhesive, coagulant, and rheological properties of blood; permeability of vascular wall and dialyses of surrounding tissues. Dysfunctions in these signaling pathways not only result in the loss of important homeostatic functions but also engage endothelium into the propathological activities. This pattern shows the two sides of the coin; thus endothelium might be either good or bad guy depending on the default signaling. Endothelial dysfunction was observed in aging as well as in major lifestyle-related diseases. This suggests that the endothelium can serve as a target for prevention and treatment of diseased states. Currently there is an intensive development in identification of new endothelium-dependent signaling pathways and characterization of their role for various pathological states and disease development. This issue aims at helping this progress.

We invite investigators to contribute original research articles as well as review articles that document the role of endothelium in maintenance of physiological functions as well as in development of diseased states. We are also interested in studies investigating the risk factors in endothelial dysfunction development or aimed at its prevention and treatment. Potential topics include, but are not limited to:

  • New mechanistic insights into action of endothelium-derived relaxing and contracting factors, oxidative and nitrosative stress
  • New methods in determination of endothelial dysfunction and vascular cell-to-cell communication
  • Risk factors in development of endothelial dysfunction: fetal programming, stress, and obesity
  • Endothelial alterations in diseased states: hypertension, atherosclerosis, coronary heart disease, diabetes, renal disorders, brain disorders, and hypoxic conditions
  • New approaches in prevention and therapy of endothelial dysfunction: diet, exercise, and new drugs

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/bmri/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/bmri/cardiology/edss/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 810436
  • - Editorial

Endothelium in Diseased States

Iveta Bernatova | Ramaroson Andriantsitohaina | ... | Vladimir V. Matchkov
  • Special Issue
  • - Volume 2014
  • - Article ID 640329
  • - Research Article

Mas-Mediated Antioxidant Effects Restore the Functionality of Angiotensin Converting Enzyme 2-Angiotensin-(1–7)-Mas Axis in Diabetic Rat Carotid

Larissa Pernomian | Mayara Santos Gomes | ... | Ana Maria de Oliveira
  • Special Issue
  • - Volume 2014
  • - Article ID 985813
  • - Review Article

The Endothelium, A Protagonist in the Pathophysiology of Critical Illness: Focus on Cellular Markers

Sabrina H. van Ierssel | Philippe G. Jorens | ... | Viviane M. Conraads
  • Special Issue
  • - Volume 2014
  • - Article ID 531087
  • - Research Article

Short-Term Esmolol Improves Coronary Artery Remodeling in Spontaneously Hypertensive Rats through Increased Nitric Oxide Bioavailability and Superoxide Dismutase Activity

Ana Arnalich-Montiel | María Carmen González | ... | Begoña Quintana-Villamandos
  • Special Issue
  • - Volume 2014
  • - Article ID 658479
  • - Research Article

Age-Related Alterations in Endothelial Function of Femoral Artery in Young SHR and WKY Rats

Angelika Puzserova | Veronika Ilovska | ... | Iveta Bernatova
  • Special Issue
  • - Volume 2014
  • - Article ID 327395
  • - Clinical Study

Endothelial Function Increases after a 16-Week Diet and Exercise Intervention in Overweight and Obese Young Women

Lisa M. Cotie | Andrea R. Josse | ... | Maureen J. MacDonald
  • Special Issue
  • - Volume 2014
  • - Article ID 598271
  • - Review Article

Endothelial Dysfunction in Experimental Models of Arterial Hypertension: Cause or Consequence?

Iveta Bernatova
  • Special Issue
  • - Volume 2014
  • - Article ID 923805
  • - Review Article

Recent Insights in the Paracrine Modulation of Cardiomyocyte Contractility by Cardiac Endothelial Cells

Jacques Noireaud | Ramaroson Andriantsitohaina
  • Special Issue
  • - Volume 2014
  • - Article ID 193095
  • - Review Article

Nitric Oxide, Oxidative Stress, and Interplay in Diabetic Endothelial Dysfunction

Alessandra Magenta | Simona Greco | ... | Fabio Martelli
  • Special Issue
  • - Volume 2014
  • - Article ID 413629
  • - Research Article

Genotype-Related Effect of Crowding Stress on Blood Pressure and Vascular Function in Young Female Rats

Peter Slezak | Angelika Puzserova | ... | Iveta Bernatova
BioMed Research International
 Journal metrics
Acceptance rate31%
Submission to final decision67 days
Acceptance to publication30 days
CiteScore3.600
Impact Factor2.276
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