The aim of this study was to examine the effects of resistance training on hematological blood markers in older individuals. Twenty-nine men and women participated to this study. Subjects were randomized in 2 groups: (1) control (<svg     style="vertical-align:-0.1638pt;width:44.400002px;" id="M1" height="11.125" version="1.1" viewBox="0 0 44.400002 11.125" width="44.400002"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
    
        
            <g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path id="x1D45B" d="M495 86q-46 -47 -87 -72.5t-63 -25.5q-43 0 -16 107l49 210q7 34 8 50.5t-3 21t-13 4.5q-35 0 -109.5 -72.5t-115.5 -140.5q-21 -75 -38 -159q-50 -10 -76 -21l-6 8l84 340q8 35 -4 35q-17 0 -67 -46l-15 26q44 44 85.5 70.5t64.5 26.5q35 0 10 -103l-24 -98h2&#xA;q42 56 97 103.5t96 71.5q46 26 74 26q9 0 16 -2.5t14 -11.5t9.5 -24.5t-1 -44t-13.5 -68.5q-30 -117 -47 -200q-4 -19 -3.5 -25t6.5 -6q21 0 70 48z" /></g><g transform="matrix(.017,-0,0,-.017,13.305,10.862)"><path id="x3D" d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" /></g><g transform="matrix(.017,-0,0,-.017,28.008,10.862)"><path id="x31" d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" /></g><g transform="matrix(.017,-0,0,-.017,36.168,10.862)"><path id="x33" d="M285 378v-2q65 -13 102 -54.5t37 -97.5q0 -57 -30.5 -104.5t-74 -75t-85.5 -42t-72 -14.5q-31 0 -59.5 11t-40.5 23q-19 18 -16 36q1 16 23 33q13 10 24 0q58 -51 124 -51q55 0 88 40t33 112q0 64 -39 96.5t-88 32.5q-29 0 -64 -11l-6 29q77 25 118 57.5t41 84.5&#xA;q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" /></g>

        
    
</svg>) and (2) resistance training (<svg     style="vertical-align:-0.1638pt;width:44.400002px;" id="M2" height="11.225" version="1.1" viewBox="0 0 44.400002 11.225" width="44.400002"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
    
        
            <g transform="matrix(.017,-0,0,-.017,.062,10.963)"><use xlink:href="#x1D45B"/></g><g transform="matrix(.017,-0,0,-.017,13.305,10.963)"><use xlink:href="#x3D"/></g><g transform="matrix(.017,-0,0,-.017,28.008,10.963)"><use xlink:href="#x31"/></g><g transform="matrix(.017,-0,0,-.017,36.168,10.963)"><path id="x36" d="M137 343l67 33q37 17 63 17q79 0 129.5 -53t50.5 -131q0 -92 -58 -156.5t-147 -64.5t-147 68t-58 182q0 63 17 119t43 95.5t61.5 72t69 52t67.5 31.5q62 22 128 33l6 -32q-56 -11 -108 -35q-149 -71 -184 -231zM227 337q-47 0 -95 -27q-6 -23 -6 -70q0 -93 36 -155.5&#xA;t96 -62.5q53 0 78 45.5t25 105.5q0 68 -35 116t-99 48z" /></g>

        
    
</svg>). At baseline and after the intervention, subjects were submitted to a blood sample to determine their hematological profile (red blood cells, hemoglobin, hematocrit, platelets, leukocytes, neutrophils, lymphocytes, monocytes, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width). At baseline, no difference was observed between groups. Moreover, we found no significant difference after the intervention on any of these markers. A 6-month resistance program in healthy older individuals seems to have no beneficial nor deleterious effects on hematological blood parameters. However, resistance training was well tolerated and should be recommended for other health purposes. Further studies are needed to confirm these results in a large population.

Florian Bobeuf

Mélissa Labonté

Abdelouahed Khalil

Isabelle J. Dionne

Effect of Resistance Training on Hematological Blood Markers in Older Men and Women: A Pilot Study

Life history theory proposes that early-life cues induce highly integrated responses in traits associated with energy partitioning, maturation, reproduction, and aging such that the individual phenotype is adaptively more appropriate to the anticipated environment. Thus, maternal and/or neonatally derived nutritional or endocrine cues suggesting a threatening environment may favour early growth and reproduction over investment in tissue reserve and repair capacity. These may directly affect longevity, as well as prioritise insulin resistance and capacity for fat storage, thereby increasing susceptibility to metabolic dysfunction and obesity. These shifts in developmental trajectory are associated with long-term expression changes in specific genes, some of which may be underpinned by epigenetic processes. This normative process of developmental plasticity may prove to be maladaptive in human environments in transition towards low extrinsic mortality and energy-dense nutrition, leading to the development of an inappropriate phenotype with decreased potential for longevity and/or increased susceptibility to metabolic disease.

Deborah M. Sloboda

Alan S. Beedle

Cinda L. Cupido

Peter D. Gluckman

Mark H. Vickers

Impaired Perinatal Growth and Longevity: A Life History Perspective

<i  >Objective</i>. The purpose of this study was to investigate prognostic impact of cholesterol and its subfractions among 75-year-old people from the general population. <i  >Methods and Results</i>. The study comprised a random sample (222 women and 210 men) from the general population (participation rate 70&#x25;). During 10-year follow-up, 19&#x25; of women and 35&#x25; of men experienced a major cardiovascular event (MCVE). The all-cause mortality was 29&#x25; for women and 47&#x25; for men. After adjustment for cardiovascular risk factors, a low level of high-density lipoprotein cholesterol (HDL-C) was significantly associated with MCVE (<svg     style="vertical-align:-0.1638pt;width:58.712502px;" id="M1" height="11.375" version="1.1" viewBox="0 0 58.712502 11.375" width="58.712502"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><path id="x1D443" d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5&#xA;t-10.5 -39.5l-43 -241q37 -13 83 -13q67 0 125.5 45t58.5 129z" /></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><path id="x3D" d="M535 323h-483v50h483v-50zM535 138h-483v50h483v-50z" /></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><path id="x2E" d="M113 -12q-24 0 -39.5 16t-15.5 42q0 24 16 40.5t40 16.5t40 -16.5t16 -40.5q0 -26 -16 -42t-41 -16z" /></g><g transform="matrix(.017,-0,0,-.017,34.162,11.112)"><path id="x30" d="M241 635q53 0 94 -28.5t63.5 -76t33.5 -102.5t11 -116q0 -58 -11 -112.5t-34 -103.5t-63.5 -78.5t-94.5 -29.5t-95 28t-64.5 75t-34.5 102.5t-11 118.5q0 58 11.5 112.5t34.5 103t64.5 78t95.5 29.5zM238 602q-32 0 -55.5 -25t-35.5 -68t-17.5 -91t-5.5 -105&#xA;q0 -76 10 -138.5t37 -107.5t69 -45q32 0 55.5 25t35.5 68.5t17.5 91.5t5.5 105t-5.5 105.5t-18 92t-36 68t-56.5 24.5z" /></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><use xlink:href="#x30"/></g><g transform="matrix(.017,-0,0,-.017,50.481,11.112)"><path id="x36" d="M137 343l67 33q37 17 63 17q79 0 129.5 -53t50.5 -131q0 -92 -58 -156.5t-147 -64.5t-147 68t-58 182q0 63 17 119t43 95.5t61.5 72t69 52t67.5 31.5q62 22 128 33l6 -32q-56 -11 -108 -35q-149 -71 -184 -231zM227 337q-47 0 -95 -27q-6 -23 -6 -70q0 -93 36 -155.5&#xA;t96 -62.5q53 0 78 45.5t25 105.5q0 68 -35 116t-99 48z" /></g>

		
	
</svg>) and mortality (<svg     style="vertical-align:-0.1638pt;width:58.712502px;" id="M2" height="11.375" version="1.1" viewBox="0 0 58.712502 11.375" width="58.712502"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><use xlink:href="#x1D443"/></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><use xlink:href="#x3D"/></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><use xlink:href="#x2E"/></g><g transform="matrix(.017,-0,0,-.017,34.162,11.112)"><use xlink:href="#x30"/></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><path id="x31" d="M384 0h-275v27q67 5 81.5 18.5t14.5 68.5v385q0 38 -7.5 47.5t-40.5 10.5l-48 2v24q85 15 178 52v-521q0 -55 14.5 -68.5t82.5 -18.5v-27z" /></g><g transform="matrix(.017,-0,0,-.017,50.481,11.112)"><use xlink:href="#x31"/></g>

		
	
</svg>) in men but not in women. The prognostic sex disparity was nearly significant (<svg     style="vertical-align:-0.1638pt;width:58.712502px;" id="M3" height="11.375" version="1.1" viewBox="0 0 58.712502 11.375" width="58.712502"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.017,-0,0,-.017,.062,11.112)"><use xlink:href="#x1D443"/></g><g transform="matrix(.017,-0,0,-.017,15.582,11.112)"><use xlink:href="#x3D"/></g><g transform="matrix(.017,-0,0,-.017,30.286,11.112)"><use xlink:href="#x2E"/></g><g transform="matrix(.017,-0,0,-.017,34.162,11.112)"><use xlink:href="#x30"/></g><g transform="matrix(.017,-0,0,-.017,42.321,11.112)"><path id="x35" d="M153 550l-26 -186q79 31 111 31q90 0 141.5 -51t51.5 -119q0 -93 -89 -166q-85 -69 -173 -71q-32 0 -61.5 11.5t-41.5 23.5q-18 17 -17 34q2 16 22 33q14 9 26 -1q61 -50 124 -50q60 0 93 43.5t33 104.5q0 69 -41.5 110t-121.5 41q-53 0 -102 -20l38 305h286l6 -8&#xA;l-26 -65h-233z" /></g><g transform="matrix(.017,-0,0,-.017,50.481,11.112)"><use xlink:href="#x31"/></g>

		
	
</svg> for MCVE and .067 for mortality). The associations of adjusted HDL-C to MCVE and mortality were unchanged after excluding individuals with prevalent stroke or MI. Total cholesterol and low-density lipoprotein cholesterol (LDL-C) were not significantly related to prognosis in either sex. <i  >Main Conclusions</i>. HDL-C was associated with dismal prognosis in men but not in women. Elderly men with HDL-C&#x2009;&#x2009;<svg     style="vertical-align:-0.1638pt;width:31.137501px;" id="M4" height="11.125" version="1.1" viewBox="0 0 31.137501 11.125" width="31.137501"  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg">
	
		
			<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path id="x3C" d="M512 -3l-437 233v51l437 233v-58l-378 -200v-2l378 -199v-58z" /></g><g transform="matrix(.017,-0,0,-.017,14.749,10.862)"><path id="x34" d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" /></g><g transform="matrix(.017,-0,0,-.017,22.909,10.862)"><use xlink:href="#x30"/></g>

		
	
</svg>&#x2009;mg/dL deserve particular attention for cardiovascular prevention.

Göran Nilsson

John Öhrvik

Ingemar Lönnberg

Pär Hedberg

Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C,  and LDL-C

Insulin degrading enzyme (IDE) degrades amyloid <svg style="vertical-align:-2.29482pt;width:8.8500004px;" id="M1" height="13.425" version="1.1" viewBox="0 0 8.8500004 13.425" width="8.8500004"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,13.425)">
		<g transform="translate(72,-61.26)">
			<text transform="matrix(1,0,0,-1,-71.95,63.6)">
				<tspan style="font-size: 12.50px; " x="0" y="0">𝛽</tspan>
			</text>

		</g>
	</g>
</svg> (A<svg style="vertical-align:-2.29482pt;width:8.8500004px;" id="M2" height="13.425" version="1.1" viewBox="0 0 8.8500004 13.425" width="8.8500004"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,13.425)">
		<g transform="translate(72,-61.26)">
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				<tspan style="font-size: 12.50px; " x="0" y="0">𝛽</tspan>
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		</g>
	</g>
</svg>), which may inhibit the accumulation of A<svg style="vertical-align:-2.29482pt;width:8.8500004px;" id="M3" height="13.425" version="1.1" viewBox="0 0 8.8500004 13.425" width="8.8500004"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,13.425)">
		<g transform="translate(72,-61.26)">
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				<tspan style="font-size: 12.50px; " x="0" y="0">𝛽</tspan>
			</text>

		</g>
	</g>
</svg> in a brain affected with dementia of Alzheimer&#x27;s type (DAT). A decrease in the activity of IDE results in changes in glucose utilization in the brain, which could affect the cognitive and psychiatric symptoms of DAT. We investigated a possible association of IDE gene polymorphism and the behavioral and psychological symptoms of dementia (BPSD) in mild DAT. The genotyping for IDE and apolipoprotein E (ApoE) was determined in 207 patients with mild DAT and 215 controls. The occurrence of BPSD was demonstrated using the Behavioral Pathology in Alzheimer&#x27;s Disease Rating Scale (BEHAVE-AD). IDE gene polymorphism is unlikely to play a substantial role in conferring susceptibility to DAT, but it may be involved in the development of affective disturbance through the course of mild DAT, regardless of the presence of an ApoE <svg style="vertical-align:-0.13794pt;width:7.6875px;" id="M4" height="7.1875" version="1.1" viewBox="0 0 7.6875 7.1875" width="7.6875"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,7.1875)">
		<g transform="translate(72,-66.25)">
			<text transform="matrix(1,0,0,-1,-71.95,66.44)">
				<tspan style="font-size: 12.50px; " x="0" y="0">𝜀</tspan>
			</text>

		</g>
	</g>
</svg>4 allele. The present data could be the result of a small sample size. Further investigations using larger samples are thus required to clarify the correlation between IDE gene polymorphism, susceptibility to DAT, and emergence of BPSD.

Noriko Sato

Akinori Ueki

Hideo Ueno

Hidetaka Shinjo

Yoshio Morita

IDE Gene Polymorphism Influences on BPSD in Mild Dementia of Alzheimer&#39;s Type

We summarize here the studies examining the association between thyroid function and
 cognitive performance from an aging perspective. The available data suggest that there may be a continuum
  in which cognitive dysfunction can result from increased or decreased concentrations of thyroid 
  hormones. Clinical and subclinical hypothyroidism as well as hyperthyroidism in middle-aged and elderly 
  adults are both associated with decreased cognitive functioning, especially memory, visuospatial organization, 
  attention, and reaction time.  Mild variations of thyroid function, even within normal limits, can have significant 
  consequences for cognitive function in the elderly. Different cognitive deficits possibly related to thyroid failure 
  do not necessarily follow a consistent pattern, and L-thyroxine treatment may not always completely restore 
  normal functioning in patients with hypothyroidism.  There is little or no consensus in the literature regarding 
  how thyroid function is associated with cognitive performance in the elderly.

M. E. B&#233;gin

M. F. Langlois

D. Lorrain

S. C. Cunnane

Thyroid Function and Cognition during Aging

<i  >Background</i>. The aim of the present study was to investigate the relationships between personality and quality of life during the course of geriatric rehabilitation, against the background of Cloninger&#x27;s biosocial theory of personality. <i  >Methods</i>. All consecutive patients of a geriatric rehabilitation clinic during one year were evaluated at admission and discharge (<svg style="vertical-align:-0.17555pt;width:54.237499px;" id="M1" height="11.0375" version="1.1" viewBox="0 0 54.237499 11.0375" width="54.237499"  xmlns="http://www.w3.org/2000/svg">
	<g transform="matrix(1.25,0,0,-1.25,0,11.0375)">
		<g transform="translate(72,-63.17)">
			<text transform="matrix(1,0,0,-1,-71.95,63.4)">
				<tspan style="font-size: 12.50px; " x="0" y="0">N</tspan>
				<tspan style="font-size: 12.50px; " x="12.490497" y="0">=</tspan>
				<tspan style="font-size: 12.50px; " x="24.530886" y="0">6</tspan>
				<tspan style="font-size: 12.50px; " x="30.782387" y="0">8</tspan>
				<tspan style="font-size: 12.50px; " x="37.033886" y="0">7</tspan>
			</text>

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	</g>
</svg>) by means of the &#x2018;&#x2018;Vienna List&#x2019;&#x2019; (a newly developed questionnaire for the assessment of quality of life in patients with severe dementia), and two variants of the Temperament and Character Inventory. 
<i  >Results</i>. Self-directedness showed the most general and highest impact on quality of life and successful rehabilitation. <i  >Conclusions</i>. It is probable in old and very old individuals who are on their highest level of maturity that the character represents the most important regulatory system in the encounter with challenges of daily life, which necessitates rehabilitation.

J&#246;rg Richter

Martina Schwarz

Barbara Bauer

Personality Characteristics Determine Health-Related 
                        Quality of Life as an Outcome Indicator of Geriatric Inpatient Rehabilitation

Cobalamin (vitamin B12) deficiency is particularly common in the elderly (&gt;65 years of age) but is often unrecognized because its clinical manifestations are subtle; however, they are also potentially serious, particularly from a neuropsychiatric and hematological perspective. In the elderly, the main causes of cobalamin deficiency are pernicious anemia and food-cobalamin malabsorption. Food-cobalamin malabsorption syndrome is a disorder characterized by the inability to release cobalamin from food or its binding proteins. This syndrome is usually caused by atrophic gastritis, related or unrelated to <i>Helicobacter pylori</i> infection, and long-term ingestion of antacids and biguanides. Management of cobalamin deficiency with cobalamin injections is currently well documented but new routes of cobalamin administration (oral and nasal) are being studied, especially oral cobalamin therapy for food-cobalamin malabsorption.

Emmanuel Andrès

Thomas Vogel

Laure Federici

Jacques Zimmer

Ecaterina Ciobanu

Georges Kaltenbach

Cobalamin Deficiency in Elderly Patients: A Personal View

Genetic and biochemical studies have shown that PARP-1 and poly(ADP-ribosyl)ation play an important role in DNA repair, genomic stability, cell death, inflammation, telomere maintenance, and suppressing tumorigenesis, suggesting that the homeostasis of poly(ADP-ribosyl)ation and PARP-1 may also play an important role in aging. Here we show that PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M1" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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				<tspan style="font-size: 8.75px; " x="8.4281759" y="0">−</tspan>
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</svg> mice exhibit a reduction of life span and a significant increase of population aging rate. Analysis of noninvasive parameters, including body weight gain, body temperature, estrous function, behavior, and a number of biochemical indices suggests the acceleration of biological aging in PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M2" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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				<tspan style="font-size: 8.75px; " x="8.4281759" y="0">−</tspan>
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</svg> mice. The incidence of spontaneous tumors in both PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M3" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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</svg> and PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M4" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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</svg> groups is similar; however, malignant tumors including uterine tumors, lung adenocarcinomas and hepatocellular carcinomas, develop at a significantly higher frequency in PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M5" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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</svg> mice than PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M6" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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</svg> mice (72&#x25; and 49&#x25;, resp.; <svg style="vertical-align:-0.30096pt;width:24.450001px;" id="M7" height="10.7" version="1.1" viewBox="0 0 24.450001 10.7" width="24.450001"  xmlns="http://www.w3.org/2000/svg">
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				<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
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</svg> .05). In addition, spontaneous tumors appear earlier in PARP-<svg style="vertical-align:-0.0pt;width:26.5875px;" id="M8" height="13.9875" version="1.1" viewBox="0 0 26.5875 13.9875" width="26.5875"  xmlns="http://www.w3.org/2000/svg">
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</svg> mice compared to the wild type group. Histopathological studies revealed a wide spectrum of tumors in uterus, ovaries, liver, lungs, mammary gland, soft tissues, and lymphoid organs in both groups of the mice. These results demonstrate that inactivation of DNA repair gene PARP-1 in mice leads to acceleration of aging, shortened life span, and increased spontaneous carcinogenesis.

Tatiana S. Piskunova

Maria N. Yurova

Anton I. Ovsyannikov

Anna V. Semenchenko

Mark A. Zabezhinski

Irina G. Popovich

Zhao-Qi Wang

Vladimir N. Anisimov

Deficiency in Poly(ADP-ribose) Polymerase-1 (PARP-1) Accelerates Aging and Spontaneous Carcinogenesis in Mice

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<p><em>Current Gerontology and Geriatrics Research</em> publishes research based on molecular, cellular, organismal aspects of gerontological research and in diagnosis, treatment, evaluation and educational aspects of geriatrics research.</p>


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Current Gerontology and Geriatrics Research publishes research based on molecular, cellular, organismal aspects of gerontological research and in diagnosis, treatment, evaluation and educational aspects of geriatrics research.

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Current Gerontology and Geriatrics Research

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