In recent years, patients with chronic kidney disease (CKD) and metabolic syndrome (MetS) appear to be increasing along with increasing cardiovascular diseases in industrial countries. In order to ameliorate cardiovascular mortality, it is essential to extend comprehensive treatments for patients with CKD and MetS. Although those disorders may be partly formed by a certain common pathological basis, there is insufficient knowledge of the underlying interplay between the pathological conditions and cardiovascular diseases. In this special issue, we are going to invite front-line researchers and authors to submit original research and review articles that explore the interaction dynamics of CKD, MetS, and cardiovascular diseases. Therefore, we are interested in articles that provide pivotal and/or novel evidence for understanding the pathophysiological relationship among the disorders and propose new strategies for treating these conditions on a clinical and molecular basis. Potential topics include, but are not limited to:

• Influence of aberrant circadian rhythm
• Pathophysiology of adipocyte-secreted factors
• Role of inflammation and oxidative stress
• Interactions of remote organs (central nervous system, digestive organs, cardiovascular system, fat tissue, etc.)
• Importance of sympathetic nervous system
• New aspects of the renin-angiotensin system
• Novel and notable biomarkers and endogenous factors

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/crp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable: