Review Article

Large Dosage of Chishao in Formulae for Cholestatic Hepatitis: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

Author (reference)Published yearCases T/C Age (years) 
Range, mean
Sex 
Male/female
Course of disease (years) 
Range, mean

Tang et al. [14]201350/50 T: 24–65, 41.2 
C: 23–67, 42.1
T: 37/13
C: 38/12
T: 0–0.7, 0.4
C: 0–0.8, 0.4
Chen and Tu [15]201330/20 NRT: 20/10
C: 15/5
NR
Wu [16]201245/45 T: 33–68, 47.9 
C: 34–66, 48.4 
T: 26/19
C: 23/22
T: 1–6, 3.4
C: 1–7, 3.1
Xu et al. [17]201130/30 T: 18–53, 42.2 
C: 16–58, 45.3
T: 18/12
C: 20/10
T: 0.1–3
C: 0.1–3.2
Zhu [18]201045/45 T: 22–75, 44.6 
C: 34–68, 46.1
T: 20/25
C: 22/23
T: 0.1–0.4
C: 0.1–0.3
He et al. [19]200832/28 T: 16–61, 32 
C: 17–59, 31
T: 19/13
C: 16/12
NR
Xie et al. [20]200830/30 T: 22–61, 38.5 
C: 19–65, 42.1
T: 22/8
C: 20/10
T: 0.1–6, 4.5
C: 0–10, 4.7
Shu [21]200724/2419–53 T: 36.2 
C: 37.8
T: 20/4
C: 18/6
T: 0.2
C: 0.2
Li [22]200632/31 T: 37.1 
C: 37.3
T: 22/10
C: 17/14
T: 0.1
C: 0.1
He et al. [23]2003121/117 NRNRNR
He* et al. [24]2003312/104 T: 39.8 
C: 41.3
T: 233/79
C: 80/24
T: 0.1a, 3.1ch
C: 0.1a, 3.3ch

T: trials group, C: control group. NR: no report. aacute cholestatic hepatitis, chchronic cholestatic hepatitis.
“∗” in Table 1 and Table 2 refers to another study different from the study of the same name and year’