Network Pharmacology Analysis of Traditional Chinese Medicine Formula Xiao Ke Yin Shui Treating Type 2 Diabetes Mellitus

Figure 2

Protein-protein interaction networks. The mapping of PPI network was generated by the STRING server. (a) PPI network of genes regulated by XKYS formula (217 nodes, 2070 edges). (b) PPI network of genes relating to the pathophysiology of T2DM (602 nodes, 11595 edges). (c) 76 main target genes regulated by XKYS formula in the treatment of T2DM and its complications. This network contains 76 nodes and 333 edges. As shown in the color bar, nodes in red could be considered as important and nodes in green are less important in this network. The degree value of each node in Figure 2(c) is presented in Table 3.

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