Observational Study of Qigong as a Complementary Self-Care Practice at a Tertiary-Care Pain Management Unit

Curry, Lauren; Pike, Meghan; Lynch, Mary; Marcon, Dana; Sawynok, Jana

doi:https://doi.org/10.1155/2021/6621069

Evidence-Based Complementary and Alternative Medicine

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Abstract Introduction Methods Results Discussion Conclusions Abbreviations Data Availability Ethical Approval Consent Conflicts of Interest Authors’ Contributions Acknowledgments References Copyright Related Articles

Research Article | Open Access

Volume 2021 | Article ID 6621069 | https://doi.org/10.1155/2021/6621069

Observational Study of Qigong as a Complementary Self-Care Practice at a Tertiary-Care Pain Management Unit

Lauren Curry,¹Meghan Pike,²Mary Lynch,³Dana Marcon,⁴and Jana Sawynok⁵

Academic Editor: Susana Gorzalczany

Received04 Nov 2020

Accepted01 Jun 2021

Published19 Jun 2021

Abstract

Qigong, which can be characterized in many different ways, is offered as a complementary self-care practice at a tertiary-care pain management unit in Halifax, Nova Scotia. This report provides a quantitative and qualitative assessment of two groups engaged in qigong practice in this context as part of two Research in Medicine (RIM) projects (2014-15, 2016-17). It includes assessments of pain, mood, quality of life, sleep, and fatigue, considers outcomes in relation to the amount of practice, and considers whether health attitudes would help determine who might benefit from the practice. There were 43 participants (28 ongoing practitioners, 15 new to qigong). The ongoing practice group in RIM2 had significant benefits over time in pain, mood, quality of life, and fatigue in quantitative scores, but changes were not significant in RIM 1. There were no differences in any measures in those new to qigong. Qualitative comments in core and other domains reflected good or better outcomes in 16 subjects in the ongoing group who practiced consistently. In those who practiced less, results were more variable. In most of those new to qigong, the practice was limited and comments indicate minimal changes. Those engaged in qigong have a stronger internal health locus of control than control subjects. Diligent qigong practice provides multiple health benefits for those with chronic pain, and qualitative assessments are essential for documenting these effects. For those new to qigong, factors needed to effectively engage practice need to be explored further to optimize program delivery. The trial is registered with http://www.clinicaltrials.gov (NCT04279639).

1. Introduction

Qigong is a traditional Chinese practice involving specific movements, breathing methods, and meditation and is promoted for health maintenance and improvement. Since the 1980s, and particularly since 2000, there has been considerable interest in qigong as a potential therapeutic modality. Contemporary descriptions of qigong include traditional Chinese exercise [1], therapeutic exercise [2], mindfulness-based exercise [3, 4], mind-body therapy [5], meditative movement [6], and movement-based embodied contemplative practice [7]. Qigong is being examined in multiple health domains and is emerging as a promising complementary practice in several areas (cancer treatment, respiratory disorders, cardiovascular disorders, and movement disorders) [2]. There are also beneficial effects on chronic pain, fatigue and sleep, and mood disorders [1, 3–5].

Fibromyalgia is a chronic pain condition with common comorbidities of sleep and mood disorders [8]. In 2012, we published a controlled trial of qigong for fibromyalgia involving two groups of subjects (immediate and delayed training groups) and reported reproducible and significant benefits in pain, sleep, impact, and physical and mental function [9]. Benefits in all areas were related to the amount of practice during the 24-week trial. Some participants continued with their practice beyond the trial and attained marked health benefits [10]. Further studies on qigong for fibromyalgia at other sites (durations 6–24 weeks) indicated consistent benefits in those who engage in regular (daily or near-daily) practice but inconsistent effects with weekly sessions [11]. As a result of local experiences, qigong classes have been offered as a complementary self-care practice at a local tertiary-care pain management unit.

The present report is an observational study of participants who undertook qigong as a voluntary self-care practice at the pain management unit in Halifax, Nova Scotia. Two groups of individuals were observed (2014-2015, 2016-2017) in the context of Research in Medicine (RIM) projects by two medical students. The trial provided an opportunity to document experiences of those involved in long-term qigong practice over several years (few trials extend beyond 24 weeks) and of those new to the practice (providing insight into knowledge translation from the controlled trial). A mixed-methods approach was used, combining quantitative measures (for pain, mood, quality of life, sleep, and fatigue) and qualitative comments (open-ended comments relating to the same domains). Such approaches provide a more complete reflection of patient experiences, especially with regard to chronic pain [12, 13]. An additional questionnaire assessing health locus of control was included as the practice involves self-care and application care in practice.

The aims of the study were (a) to provide quantitative and qualitative assessments of participant experiences of qigong as a complementary practice in a real world-setting of chronic pain management, (b) to consider outcomes in relation to the amount of practice, and (c) to determine whether attitudes might be helpful for predicting who might benefit from the practice. Six of the cases from this observational trial reporting remarkable outcomes with the long-term practice of qigong have already been published as a case series [14]; the current analysis includes consideration of their quantitative and attitudinal scores as part of the entire group.

2. Methods

2.1. General

This study represents two observational intervals of those who undertook qigong as a voluntary self-care practice at the Queen Elizabeth II Health Science Centre’s Pain Management Unit in Halifax, Nova Scotia, Canada. It was approved by the appropriate Research Ethics Board prior to commencement. In 2012, a published report indicated significant benefits of Chaoyi Fanhuan Qigong (CFQ), a form of qigong available locally (http://www.cfqcanada.com), in those with fibromyalgia in relation to pain and other health areas [9]. Qigong classes have been offered since 2008 when the results of a pilot trial were available. Participants entered the current study based on former experience with the practice in response to pamphlets available in the clinic reception area and by word of mouth. The report summarizes participant experiences undertaken as RIM projects between July 1, 2014 and May 31, 2015 (MP), and July 1, 2016 and May 31, 2017 (LC). The study was registered retrospectively at clinicaltrials.gov (NCT04279639).

2.2. Participants

In total, the study involved 43 subjects, with N = 29 participating in RIM1 and N = 29 in RIM2. The latter involved overlap subjects who continued from RIM1 and some who had prior experience with qigong but had not participated in RIM1. There were 15 subjects who were new to qigong (N = 4 in RIM1 and N = 11 in RIM2). Table 1 outlines the components of the trial and identifies specific numbers who participated in each component. Table 2 presents entered demographics, including gender, age, pain diagnoses, and relevant medical history.

2.3. Measures

Consistent with recommendations for chronic pain studies [15], quantitative measures included assessments of pain (BPI, Brief Pain Inventory), mood (POMS, Profile of Mood Scale), sleep (PSQI, Pittsburgh Sleep Quality Index), fatigue (CFS, Chronic Fatigue Scale), and quality of life (SF-12) [9]. In addition, qualitative comments were collected reflecting these domains (pain, sleep, other health areas, quality of life, and medications) via open-ended surveys. As there is literature indicating health benefits are related to the amount of qigong practice within a trial [9, 11, 16], participants completed weekly logs of practice times (minutes/day, days/week). The times at which data collection took place are summarized in Table 1.

In order to assess health attitudes, an additional questionnaire related to Health Locus of Control (HLC) was included. This is a set of 11 questions relating to attitudes towards the degree of control one has over illness [17], which has been used to characterize chronic pain populations [18]. In order to have a comparator group, the HLC questionnaire was also distributed to a sample of those attending the pain management unit who did not undertake qigong practice (July-Aug 2016).

2.4. Intervention

Chaoyi Fanhuan Qigong, CFQ (http://www.cfqcanada.com), consists of two levels of instruction. Level 1 consists of 7 movements, with a set consisting of 10 repetitions of movements 1–5 and 5 repetitions of movements 6-7. Each set takes approximately 15 minutes to perform. Level 2 instruction consists of meditative instruction and involves sitting, laying, and standing postures. There is also instruction in additional ancillary exercises. Weekly classes during the 6-week sessions consisted of 120 minutes of instruction and practice. Instruction was delivered by an instructor (DM) with at least 10 years of experience; she had also provided instruction in the randomized controlled trial and was experienced working with those with chronic pain [9]. Participants were encouraged to practice daily for 15–45 minutes initially and then for longer when they became more experienced. Practice times, especially longer ones, consist of a mix of level 1, level 2, and ancillary practices. Sessions were offered six times throughout the year (Table 1), and participants were encouraged to maintain their home practice between sessions.

2.5. Analysis

This study involves considerable heterogeneity and multiple viewpoints were required to assess outcomes. Quantitative measures were analysed for each interval using paired t-tests to compare outcomes for each 6-week interval to the entry value. For those new to qigong, the entered value is a true baseline (N = 4 in RIM1, N = 11 in RIM2; total N = 15) and this group is considered separately. For those with prior qigong experience, the study entry value only provides an anchor value. Qualitative assessments are presented in tables, categorized as good or variable outcomes, and constitute a narrative approach. The experiences of those new to qigong are presented separately, as the duration of their experience vastly differs from that of ongoing practitioners. HLC measures were compared to a control group (N = 46) consisting of patients attending the pain management unit who were not undertaking qigong. Only demographics and HLC information was collected from this group. Specific subgroups were compared to the control group using the unpaired t-test.

3. Results

3.1. General

The study consisted of N = 43 subjects, N = 29 in RIM1, and N = 29 in RIM2. In RIM2, 15 continued from RIM1, 11 were new to qigong, and 3 had prior qigong experience but did not participate in RIM1. Demographics are shown in Table 2. These are depicted as groups to align with quantitative data (first pair of columns) and as ongoing and new subjects to align with qualitative data and attitudinal analysis (second pair of columns). Participants were predominantly female, with mean age of 53–57 years and mean duration of chronic pain of 12–16 years. The most common forms of chronic pain were back pain and fibromyalgia. There were 4 discontinuations in RIM1 and 6 discontinuations in RIM2; these are not included in the reported numbers. There was no exact information collected, but contributing factors would be likely lack of effect, amount of effort involved, and other miscellaneous factors.

3.2. Quantitative Measures

Figure 1 presents quantitative measures for pain, mood, and quality of life Figures 1(a)–1(c) for RIM1 participants. It contains data for N = 25 ongoing subjects. The N = 4 new subjects from that cohort are included in the RIM2 data, which considers new subject experiences as a combined group (N = 15). There were no significant differences from entry values over the duration of the RIM1 trial.

(a)

(b)

(c)

Figure 1

Average pain (a), average mood (b), and quality of life (c) from the RIM1 study start to 36 weeks of practice. Lower scores indicate less pain, less depression, and lower quality of life, respectively. Numbers below x-axis indicate those completing respective 6-week sessions. There were N = 29 participants in RIM1, but the 4 new subjects are included along with RIM2 new subjects to form a single group (see Figure 2). There were no significant longitudinal differences ( paired t-test) from the trial start (week 0) at any time.

Figure 2 presents quantitative measures for pain, mood, quality of life Figures 2(a)–2(c), and sleep quality and fatigue Figures 2(d) and 2(e) for RIM2 participants. In the ongoing practice group, there were significant differences () from entered values in pain (12–24 weeks), quality of life (12–24 weeks), sleep quality (6 weeks), and fatigue (12 weeks), with all changes reflecting symptom improvements except for sleep which was transiently worse. In those new to qigong, there were no significant changes from baselines.

(a)

(b)

(c)

(d)

(e)

Figure 2

Average pain (a), average mood (b), quality of life (c), sleep quality (d), and fatigue (e) from the RIM2 study start to 36 weeks of practice. The orange line represents ongoing participants (N = 18) and the blue line new participants (N = 14). The x-axis shows the week of practice (# of ongoing, # of new). Lower scores indicate less pain, less depression, lower quality of life, improved sleep quality, and improved fatigue, respectively. Significant differences () from the trial start (week 0) are indicated as a diagonal crossover of the data point. Start values differed significantly (, marked with a horizontal crossover of the data point) for average pain rating (a) and average sleep quality (d), with new participants experiencing worse pain and poorer sleep than the ongoing participants. No other measures differed between groups from RIM2 study start to 36 weeks of practice.

3.3. Qualitative Comments

Table 3 presents qualitative comments for 10 subjects who practiced qigong for at least 3 years (RIM1, intervening year, RIM2). This group achieved good outcomes as revealed post hoc by the nature of their comments. Their experiences are in addition to N = 6 cases which are reported separately [14]. Overall, good or better outcomes were reported in 16/28 or 57% of long-term practitioners. While we use the term “good outcomes” to characterize these, many actually portray markedly improved function, including in those with chronic pain for decades who had previously accessed multiple conventional medical treatments. Most had practiced qigong for several years prior to RIM1, as noted in the table. Long-term qigong practitioners consistently reported benefits in pain, mood, sleep, and a reduced need for medications for these conditions. Additional benefits were noted in cardiovascular function (#14), asthma (#28), and psoriatic arthritis, diabetes, and bowel irregularities (#34). This group self-reported mean practice times of 78 to 118 min (∼1-2 hours) per day, daily or near-daily.

In the six cases reported separately [14], participants reported benefits in pain, mood and sleep, irritable bowel syndrome, food and environmental sensitivities, frozen shoulder, plantar fasciitis, head trauma, wrist tendonitis, immune function, respiratory function, sleep apnea, mobility, depression, anxiety, and posttraumatic stress. Most also commented on discontinuations of medications for pain and other conditions. Several commented directly on the profound nature of their health changes. This group self-reported extensive daily practice, with mean practice times of 99–190 min (∼1.5–3 hrs) per day, and consistent daily practice.

Table 4 presents qualitative comments for ongoing practitioners where outcomes were considered more variable based on a global assessment of comments (N = 13). Benefits in core domains were noted in several instances (#1, #8, #10, #19, #20, #38) and other health areas (#19 irritable bowel, #20 frozen shoulder). (This brings the total of those who experienced benefits from qigong practice to 22/28, or 78%.) Others reported little change or no benefit (#13, #25, #26). The variable group practiced for a mean of 25–38 min per day for 2–7 days per week. Some offered little in the way of comments (#4, #7, #24, #33) and reported minimal practice times (see footnote to Table 4).

Table 5 summarizes qualitative comments for those who were new to qigong when they commenced. One of these (#18) is included in Table 3 due to the nature of the outcomes and amount of practice. Most new participants attended for only a limited amount of time (1–3 sessions, 6–18 weeks) and reported minimal changes. A few noted some benefits in pain (#41, #46, #49, #52), while others comment on transient worsening of pain after classes (#39, #44, #50). New participants practiced for 34–47 min per day on 1–4 days per week.

Considered sequentially, qualitative comments published previously in a separate report [14] and in Tables 3–5 indicate a clear relationship between self-reported qigong practice times and health benefits in core and other domains. Those who practiced the most attained the most health gains. While there are imprecisions in the method of reporting practice times, even with this uncertainty, the relationship to outcomes is clear.

3.4. Attitudinal Assessments

Table 6 presents HLC scores for qigong subgroups categorized in different ways compared to control subjects attending the same facility (N = 46). Lower HLC scores indicate a stronger internal locus of control. All participants (n = 43) showed a lower HLC score compared to controls, as did ongoing qigong practitioners (N = 28). Those who were new to qigong (N = 15) trended lower compared to controls but were not significantly lower. Both those who attained good and variable outcomes were significantly lower than controls.

4. Discussion

This report documents the experiences of 43 people living with chronic pain (mean pain durations 12–15 years) who attended a tertiary-care pain management unit and undertook qigong as a self-care practice in addition to their usual medical care between 2014 and 2017. There is considerable heterogeneity in amounts of practice, both in the number of years of experience and in amounts of ongoing practice, and in outcomes as reflected in qualitative comments. Multiple viewpoints and subgroup considerations were required to derive meaningful information, and the dataset might best be considered as an extended case series. Pooled quantitative scores for pain, mood, and quality of life showed no longitudinal differences for ongoing qigong subjects during RIM1 but significant benefits during RIM2. With those new to qigong practice, there was little change in their scores. Results of the quantitative assessments are unremarkable and include many limitations in terms of standardized data collection and analysis methods. Of greater interest and importance in this study are qualitative comments related to the same domains, which provide a different view of health experiences, especially when considered as subgroups in relation to the amount of practice.

The experienced group represents those who have practiced qigong for >3 years (classes were offered each year; those continuing from RIM1 to RIM2 continued during the intervening, nonobserved year) and longer (up to 11 years). This information is of considerable value, as controlled trials for qigong in health areas relevant to chronic pain populations generally reflect durations of 6–24 weeks [3–5]. Collectively, qualitative comments consistently report benefits in core domains (pain, mood, sleep, quality of life) and multiple other diverse health benefits. Considered holistically, these outcomes can be characterized as good or very good. Some describe such profound health benefits that they can be considered remarkable and, for this reason, have been reported separately and in a more complete manner [14]. The self-reported practice times by these are considerable (1-2 hours/day near-daily or daily) (1.5–3 hours/day each day in case reports). Motivations for engaging in such extended practice times are the health benefits derived from the earlier practice and the wish to explore how far benefits can develop. In the subgroup where outcomes are variable, practice times were ∼0.5 hours/day for 2–7 days per week and are noticeably lesser than for those who reported good outcomes. Other qigong trials similarly report health benefits being related to the amount of practice within trials [9, 16] and between trials [4].

The seeming mismatch between quantitative and qualitative assessments for the ongoing practice group requires consideration. For these participants, entered values against which postpractice values are compared do not represent baselines due to the ongoing nature of their practice. In absolute terms, entered pain levels are in the moderate range and less than those in the new group and those in a larger trial of fibromyalgia subjects [9]. This factor applies to all quantitative measures. While mean entered values for ongoing participants compared to new participants reflect greater symptomatology in all instances for the new group (Figure 2), only the pain and sleep quality values differed significantly. Quantitative scores are widely used for evaluating pain outcomes, have been repeatedly validated, and provide important information for decision making. Nevertheless, the mismatch between the two approaches supports the need for pluralistic views on how to reflect health experiences of those with chronic pain [12, 13], especially when longer-term assessments are involved.

Those new to qigong must be considered separately, as their experiences with the practice differ vastly from others, and the aims of considering their outcomes differ. One new participant practiced diligently throughout, had good outcomes, and is included along with ongoing practitioners. Others attended only limited numbers of sessions and had lower daily and weekly practice times. Their outcomes are not as good as outcomes at 8–16 weeks in the controlled trial of this form of qigong in fibromyalgia [9]. The two groups had similar ages and durations of chronic pain. There are, however, differences in the method of delivery of instruction in these contexts. In the controlled trial, the training groups were all new to qigong at the same time, attended an orientation session that indicated health professional support, and received initial instruction in a more intensive manner (2 half-days, 8 hours). In the current setting, there was no orientation session, and new participants mixed with those who were experienced in weekly sessions (it can take 6–12 weeks before they are comfortable with techniques). Factors needed to encourage initiation and maintenance of practice need to be explored. Despite these considerations, it is important to recognize that some of the ongoing group in this report did encounter the practice through this delivery method, so it can be effective. (Others in the ongoing group encountered the practice through the trials, community-based practice, or prior exposure to pain self-management techniques.) The design of optimal program delivery requires careful consideration.

With regard to mechanisms by which health benefits occur, contemporary viewpoints consider endocrine, immune, and inflammatory biology mediation of mind-body therapies in general [19] and qigong in particular [20]. Recent neuroimaging of qigong in older adults indicates that practice affects brain regional and network activity [21], supporting earlier reports suggesting qigong modifies brain function [22–24]. A large trial involving functional magnetic resonance imaging of qigong in fibromyalgia subjects is currently underway (http://www.clinicaltrials.gov, NCT03890133) and should contribute to understanding neurobiological changes resulting from qigong practice in those with chronic pain. Chronic pain involves central sensitization (augmented signaling, diminished modulation) [25] and a shift in central pathways from nociceptive to emotional circuits [26, 27], and pain improvement reported by long-term qigong practitioners would likely be reflected in such changes. With inflammatory biology proposed as a key link in mind-body therapies [19], it is interesting to note that in those who practice qigong for 1–5 years (akin to experiences of some subjects in this study), there are alterations in the genomic expression of targets involved in the resolution of inflammation [28]. Furthermore, chronic pain is associated with disturbances in parasympathetic regulation [29], and as qigong promotes parasympathetic activity [30], this provides an additional potential mechanism for improvement to occur. Finally, the benefits of qigong in diverse health areas as noted by participants in this study, and especially in the six cases reported separately [14], indicate that qigong must restore integrative function and autoregulation, as elaborated in systems biology approaches [31].

The current study included an assessment of HLC. A more internal locus is associated with better outcomes with pain and depression [32, 33]. The qigong group held a more internal health locus compared to a control group. This is to be expected for a group that engages in a self-care practice, especially for such amounts of practice. All qigong subgroups differed from the control group, except those new to qigong simply showing a trend. It is not clear whether the loci of control scores change over time, but this could occur as a result of experience. Both control and qigong group HLC values in this study (means 36.07 and 31.79, respectively) are lower than those in other chronic pain studies using the same measure (fibromyalgia 45.73; rheumatoid arthritis 40.12) [18]; this may reflect differences in groups, cultures, or times. A more internal locus of control also is associated with the use of complementary therapies [34].

5. Conclusions

This report documents multiple health benefits over time in those with chronic pain who practice qigong, with benefits related to the amount of practice. Qualitative comments are essential for portraying these effects. Qigong can be characterized in several ways (see Introduction). The language of instruction can seem strange at times; it requires considerable diligence in practice, and it is not for everyone. However, given the profound nature of changes in subgroups described in this observational trial, further exploration of the potential for benefits in multiple health areas needs to occur. Both controlled trials over a specified interval and extension trials are needed, and with the latter approach especially, qualitative comments are essential to reflect experiences more completely.

Abbreviations

BPI:	Brief Pain Inventory
CFQ:	Chaoyi Fanhuan Qigong
CFS:	Chronic Fatigue Scale
COPD:	Chronic obstructive pulmonary disease
F:	Female
HLC:	Health locus of control
M:	Male
N:	Number
NSAIDs:	Nonsteroidal anti-inflammatory drugs
POMS:	Profile of Mood Scores
PSQI:	Pittsburgh Sleep Quality Index
SF-12:	Quality of Life Survey.

Data Availability

Data are available upon request to the principal investigator.

Ethical Approval

This study was approved by the Nova Scotia Health Authority Research Ethics Board.

Each person consented to participate in the study and for study results to be published.

Conflicts of Interest

DM conducted the qigong classes for the pain management unit. She also conducts community-based qigong classes. All other authors have no conflicts of interest relevant to this study.

Authors’ Contributions

LC conducted data collection and analysis for RIM2 and assisted in manuscript development. MP developed the protocol and conducted data collection and data analysis for RIM1. ML was involved in protocol development and trial organization. DM was the qigong instructor for the trial. JS was involved in the trial organization, data analysis, and drafting the manuscript. All authors provided input into and approved the final wording.

Acknowledgments

The authors acknowledge all participants in this trial for their contributions to medical science, some of whom engaged in extraordinary amounts of practice. MP and LC received summer studentships as part of the Research in Medicine program at Dalhousie University. Qigong instruction was supported by funds from the Pain Management Unit.

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Copyright © 2021 Lauren Curry et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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