Research Article

Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats

Table 2

Effects of cafeteria diet on gene expression in the pancreas. * ≤ 0.05 and # ≤ 0.1 versus standard diet.

Standard dietCafeteria diet

Ins2 1.22 ± 0.35.37 ± 1.4*
Cpe 1.16 ± 0.33.71 ± 0.8*
Bcl-2 1.15 ± 0.30.28 ± 0.1*
Bax 1.08 ± 0.21.64 ± 0.4
Bcl-2/Bax 1.27 ± 0.50.24 ± 0.1#
Ccnd2 1.31 ± 0.41.12 ± 0.3