Formulation Optimization and Evaluation of Probiotic Lactobacillus sporogenes-Loaded Sodium Alginate with Carboxymethyl Cellulose Mucoadhesive Beads Using Design Expert Software

Figure 5

Depicts the scanning electron microscopy (SEM) images of dried beads of Lactobacillus sporogenes at different magnification, (a) Lactobacillus sporogenes-loaded batch D9, (b) cross section Of Lactobacillus sporogenes-loaded batch D9, (c) after dissolution of Lactobacillus sporogenes-loaded batch D9, and (d) cross section of after dissolution Lactobacillus sporogenes-loaded batch (D9).

(a) Lactobacillus sporogenes-loaded beads batch F-O

(b) Cross section of Lactobacillus sporogenes-loaded optimized batch

(c) After dissolution of optimized batch

(d) Cross section of after dissolution Lactobacillus sporogenes optimized batch