Research Article

Formulation Optimization and Evaluation of Probiotic Lactobacillus sporogenes-Loaded Sodium Alginate with Carboxymethyl Cellulose Mucoadhesive Beads Using Design Expert Software

Table 5

Results for stability study.

Time in daysShape of beads% probiotic entrapment efficiencySurvival of L. sporogenes (log CFU/g)
L. sporogenes free cellEncapsulated L. sporogenes beads

InitialRound93.59 ± 0.48.68 ± 0.328.59 ± 0.24
After 30 daysRound92.5 ± 0.56.88 ± 0.307.85 ± 0.23
After 60 daysRound92.09 ± 0.25.36 ± 0.247.41 ± 0.37