Transcriptomic Profiling of Human Placental Trophoblasts in Response to Infection with Enterococcus faecalis

Figure 4

Fold-change of DEGs selected for validation by real-time PCR. The housekeeping gene β-2-microglobulin was used to normalize input amounts of RNA and the levels of gene expression between coincubation samples and individual bacteria compared. The relative expression ratio for each gene is presented as a log₂ value in the histogram. A ratio greater than zero (>0) indicates upregulation of gene expression and a ratio lower than zero (<0) indicates downregulation. Error bars represent the standard deviations from triplicate analysis of each sample. Significant difference (). Values represent mean ± SD.