Research Article

Impact of Combined Acidic and Hyperosmotic Shock Conditions on the Proteome of Listeria monocytogenes ATCC 19115 in a Time-Course Study

Figure 4

Metabolic map of intermediary metabolism of L. monocytogenes ATCC 19115 under nongrowth permissive acidic and hyperosmotic conditions of pH 3.5 and aw 0.90. The map was constructed from spectral abundance data and demonstrates relative abundance of pathway components during inactivation and support data related to accumulated metabolic end-products. Pathway assignments of proteins are based on information from the KEGG database. Blue arrows indicate significant increases, and red arrows represent significant decreases in log ratio of the fold change in protein abundance proteins related to each pathway with the sampling time at 5 min, 30 min, and 1 hr at 25°C for a time-course study.