Research Article

Hypoglycemic Effect of Vitexin in C57BL/6J Mice and HepG2 Models

Figure 2

Influence of vitexin on insulin tolerance test (ITT) (a, b) and glucose tolerance test (GTT) (c, d). Mice were fed with low-fat diet (LFD), high-fat diet (HFD) or HFD supplemented with 5 mg vitexin/kg BW/day (HFD + Vitexin) for 8 weeks. Blood was collected from the tail vein, and glucose levels were determined at 0 min. Insulin (ITT) or glucose solutions (GTT) were subsequently administered by intraperitoneal injection, and the glucose level was further measured at 15, 30, 60, and 120 min after injection. Data were expressed as the mean ± SE (n = 5 − 7). Means with different letters were significantly different at .
(a)
(b)
(c)
(d)