Oxidative Medicine and Cellular Longevity

Oxidative Stress-Mediated Reperfusion Injury 2014


Status
Published

Lead Editor

1The University of Hong Kong, Pokfulam, Hong Kong

2Wright State University Boonshoft School of Medicine, Dayton, USA

3Capital University of Medical Sciences, Beijing, China

4University of Calgary, Calgary, Canada

5Sun Yat-sen University, Guangzhou, China


Oxidative Stress-Mediated Reperfusion Injury 2014

Description

Oxidative stress plays an important role in the pathogenesis of ischemia reperfusion injury. The mechanisms underlying ischaemia/reperfusion injury have been extensively studied using healthy tissues, yet less attention has been devoted to defining how the different risk factors such as diabetes and aging (situations that are associated with increased oxidative stress) may influence the degree of organ or cellular injury under pathological conditions like ischemia/reperfusion. While rapid production of large amount of reactive oxygen species (ROS), called oxidative burst, causes oxidative damage which contributes significantly to ischemia reperfusion injury, moderate elevation of ROS production induced by therapeutic interventions like ischemic or pharmacologic preconditioning may trigger cellular protective signaling pathways, leading to the attenuation of ischemia reperfusion injury.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanism underlying ischemia/reperfusion injury under normal and diseased conditions to develop strategies to treat these pathological conditions.

Potential topics include, but are not limited to:

  • Role of reactive oxygen species (ROS) in organ (heart, lung, brain, liver, kidney, and/or intestine) ischemia reperfusion injury under normal and diseased (e.g., diabetes and hypertension) conditions
  • Cellular protective signaling pathways that ROS may trigger that contribute to cellular repairing during ischemia reperfusion injury and the potential interplay between these pathways
  • Cardioprotection in aged and/or functionally impaired hearts
  • Role of reperfusion-induced oxidative stress and inflammation in mediating remote organ injury
  • Recent advances in preventing ischemia-reperfusion injury

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 481405
  • - Research Article

Protective Effects of Kaempferol against Myocardial Ischemia/Reperfusion Injury in Isolated Rat Heart via Antioxidant Activity and Inhibition of Glycogen Synthase Kinase-3

Mingjie Zhou | Huanhuan Ren | ... | Dong Wang
  • Special Issue
  • - Volume 2015
  • - Article ID 689416
  • - Editorial

Oxidative Stress-Mediated Reperfusion Injury 2014

Zhengyuan Xia | Yanfang Chen | ... | Ke-xuan Liu
  • Special Issue
  • - Volume 2015
  • - Article ID 167014
  • - Research Article

Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell Activation

Xiaoliang Gan | Dandan Xing | ... | Ziqing Hei
  • Special Issue
  • - Volume 2015
  • - Article ID 843721
  • - Research Article

Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice

Ying Jiang | Zhen Zhou | ... | Zhong-yuan Xia
  • Special Issue
  • - Volume 2015
  • - Article ID 876825
  • - Research Article

The Protective Effects of Salidroside from Exhaustive Exercise-Induced Heart Injury by Enhancing the PGC-1αNRF1/NRF2 Pathway and Mitochondrial Respiratory Function in Rats

Zheng Ping | Long-fei Zhang | ... | Xue-bin Cao
  • Special Issue
  • - Volume 2015
  • - Article ID 125106
  • - Research Article

High-Dose Polymerized Hemoglobin Fails to Alleviate Cardiac Ischemia/Reperfusion Injury due to Induction of Oxidative Damage in Coronary Artery

Qian Yang | Wei Wu | ... | Tao Li
  • Special Issue
  • - Volume 2015
  • - Article ID 287058
  • - Research Article

Effects of Cyclosporine on Reperfusion Injury in Patients: A Meta-Analysis of Randomized Controlled Trials

Kangxing Song | Shuxia Wang | Dake Qi
  • Special Issue
  • - Volume 2015
  • - Article ID 585297
  • - Research Article

Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway

Yikui Tian | Bryan A. Piras | ... | Zequan Yang
  • Special Issue
  • - Volume 2015
  • - Article ID 380403
  • - Research Article

Preventive Treatment with Ketamine Attenuates the Ischaemia-Reperfusion Response in a Chronic Postischaemia Pain Model

Suryamin Liman | Chi Wai Cheung | ... | Michael Irwin
  • Special Issue
  • - Volume 2015
  • - Article ID 590987
  • - Review Article

Oxidative Stress and Lung Ischemia-Reperfusion Injury

Renata Salatti Ferrari | Cristiano Feijó Andrade
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.900
Journal Citation Indicator0.710
Impact Factor6.543
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