Development and Physicochemical Characterization of Desonide-Loaded Nanocapsule Suspensions

Table 1

Physicochemical characteristics of desonide-loaded nanocapsule suspensions.

Formulation	D-LNC	D-NC-S100	D-NC-L100
Size (nm)	202 ± 4	163 ± 5	161 ± 4
PDI	0.19 ± 0.02	0.20 ± 0.04	0.18 ± 0.04
Zeta potential (mV)	−26.7 ± 2.0	−21.7 ± 2.3	−24.0 ± 3.6
pH	5.28 ± 0.03	3.90 ± 0.08	4.25 ± 0.06
Drug content (mg/mL)	0.48 ± 0.03	0.47 ± 0.03	0.48 ± 0.02
EE (%)	97.0 ± 2.1	98.8 ± 1.2	91.0 ± 0.9

EE: encapsulation efficiency; PDI: polydispersity index.