Research Article

Development and Physicochemical Characterization of Desonide-Loaded Nanocapsule Suspensions

Table 6

Correlation coefficient (), model selection criteria (MSC), and release exponent () obtained by fitting the release profiles of desonide according to the Korsmeyer-Peppas equation.

D-LNCD-NC-S100D-NC-L100Free-desonide

Dialysis sac
0.47 ± 0.030.33 ± 0.040.30 ± 0.030.50 ± 0.11
 MSC3.63 ± 0.254.24 ± 0.163.89 ± 0.644.19 ± 0.49
0.998 ± 0.0040.993 ± 0.0030.997 ± 0.0020.992 ± 0.004
Franz cells
0.28 ± 0.070.25 ± 0.070.29 ± 0.070.37 ± 0.04
 MSC3.25 ± 0.384.77 ± 0.544.04 ± 0.364.78 ± 0.64
0.995 ± 0.050.996 ± 0.0020.996 ± 0.0030.996 ± 0.001

Experiments were conducted with .