Antonio Mazzocca received his Medical degree from the University of Bari, Italy, in 1994, and his Ph.D. degree in clinical pathophysiology from the University of Florence, Italy, in 2001. From 2001 to 2004, he joined the Division of Cancer Biology and Angiogenesis of Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA, for the postdoctoral studies. As a Fellow, he contributed significantly to defining some aspects of the molecular biology of metastasis, with particular focus on those tumors that preferentially metastasize to the liver (i.e., colon, breast, and melanoma). His work at Harvard culminated in the identification and functional characterization of a soluble protein termed ADAM9-S (a molecule belonging to the family of ADAMs). His research has shown that this protein plays a pathogenic role in facilitating the infiltration and colonization of liver by metastatic tumors. He then moved to the Department of Pathology at the Medical Center of Vanderbilt University, Nashville, USA, where he continued to work on the pathogenesis of cancer and on issues concerning the cellular and molecular mechanisms of cancer biology and the metastatic process. He became an Investigator in 2009 at the Department of Emergency and Organ Transplantation, University of Bari Medical School. In this position, he conducted studies on liver cancer. In particular, Dr. Mazzocca’s research focuses on the study of pathogenic mechanisms involved in the remodeling of ECM during hepatocarcinogenesis, stromal tumor interactions, and cancer.
Biography Updated on 4 August 2013