Elisa Caffarelli

"Sapienza" University of Rome, Italy


Elisa Caffarelli serves as a Senior Researcher at the Institute of Molecular Biology and Pathology (IBPM) of the National Research Council (CNR) of Italy, Rome. She received her B.S. degree in biological science (summa cum laude) at the University La Sapienza of Rome in 1982. In 1984, she worked as an EMBO Fellow at the Eidgenössische Technische Hochschule (ETH) of Zürich, Switzerland. From 1984 to 1988, she served as a Research Fellow at Centro Acidi Nucleici of CNR, Rome. From 1989 to 1990, she served as an Associate Researcher of Howard Hughes Medical Institute at Yale University (USA). From 1988 to 2001, Caffarelli worked as a Researcher at Centro Acidi Nucleici of CNR, Rome, where she participated, as the first group in Italy, to the discovery of small nucleolar RNAs, encoded in introns of protein-coding genes. She also discovered and characterized a novel endoribonuclesase activity involved in RNA metabolism. Since 2001, she has been a Senior Researcher at IBPM of the CNR, Rome, leading a research group mainly interested in unveiling the mechanisms regulating gene expression at the posttranscriptional level in eukaryotes. Her present research is focused on understanding biological functions of microRNAs, long noncoding RNAs, and their roles as key regulators of neural differentiation and pathologies, as tumours (neuroblastoma) and neurodegenerative disorders (ALS). From 2012, she has been a university lecturer of epigenetic control in cellular differentiation course. She serves as a Member of the Italian Society of Biophysics and Molecular Biology (SIBBM) and serves as referee for several international journals. She authored 35 papers on highly qualified international journals and held 1 patent, extended to the United States.

Biography Updated on 31 January 2012

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