Denis Girard

Institut National de la Recherche Scientifique, Canada

Denis Girard holds Ph.D. degree in microbiology and immunology (Montreal University). He serves as Full Professor, Institut National de la Recherche Scientifique (INRS), Institut Armand-Frappier. Professor Girard is director of the research in inflammation and physiology of granulocytes laboratory. His works focus on the molecular and cellular mechanisms involved in activated neutrophils and eosinophils in response to diverse agents including cytokines, drugs, several xenobiotics, and nanoparticles and aimed at better understanding and regulating of inflammation. His research covers both in vitro and in vivo aspects of inflammation, including more recently a growing interest in other cells of myeloid origin, the monocytes-macrophages. For example, he is interested in the role of a particular groups of cytokines, interleukin (IL)-2, IL-4, IL-7, IL-9, IL-15, and IL-21, named the CD132-dependent cytokines; the role of cytoskeletal proteins during the apoptotic process in neutrophils and during efferocytosis (phagocytosis of apoptotic cells); the mechanisms involved in nanoparticle-induced apoptosis in human granulocytes; and the evaluation of the proinflammatory effects of NPs in vivo using the murine air pouch model of acute inflammation.

Biography Updated on 18 January 2015

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