Jean Sevigny

Laval University, Canada


Jean Sévigny completed his Ph.D. degree in biology in 1997 at the University of Sherbrooke under the supervision of Dr. A. R. Beaudoin with honors and was also the recipient of “The Governor General’s Academic Gold Medal of Canada.” Dr. Sévigny then moved to Boston, MA, to pursue his career at Harvard Medical School as a Research Fellow under the supervision of Dr. S. C. Robson. After two years, Dr. Sévigny was promoted to instructor in medicine at Harvard. In August 2001, he joined the “Centre de Recherche du CHU de Québec” at Université Laval, Québec, QC, Canada, where he is now Full Professor. The work of Dr. Sévigny focuses on the functions of extracellular nucleotides and the regulation of signaling through the activation of specific nucleotide receptors, termed P2-receptors. His studies have been central to the identification and cloning of the first member of a family of enzymes called nucleoside triphosphate diphosphohydrolase (NTPDase) which are responsible for regulating nucleotide/nucleoside concentrations at the cell surface. The main research interest of the laboratory of Dr. Sévigny focuses on the study of the functions of ectonucleotidases and their substrates in inflammatory processes (leukocyte migration, liver fibrosis, and IBD), liver functions, and in the vascular tone.

Biography Updated on 18 December 2016

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