Sergio Roa

Cell Biology Department, Albert Einstein College of Medicine, 1300 Morris Park Av, Bronx, New York 10461, USA


Sergio Roa received his Ph.D. degree in 2006 from the University of Salamanca in Spain, where he studied the mutagenic activation-induced cytidine deaminase (AID) enzyme and the molecular mechanisms responsible for human B-cell pathologies such as leukemia, immunodeficiency, and atopy. Then, he joined the Albert Einstein College of Medicine in New York to pursue his interest in the paradoxical role of DNA mismatch repair mechanisms, which in B cells promote AID-dependent antibody diversification but maintain global genomic stability outside of the immunoglobulin locus and are associated with susceptibility to hereditary nonpolyposis colorectal cancer.

Biography Updated on 30 November 2011

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