Vadim A. Soloshonok
Vadim A. Soloshonok was born in 1961 in Ukraine. He graduated from Kiev State University (1983) and received his Ph.D. degree (1987) from Ukrainian Academy of Sciences. He became a Research Associate of the Institute of Bioorganic Chemistry and was promoted to a Senior Research Associate (1987-1995) there. He continued his training in the area of asymmetric synthesis, in general, fluoroorganic chemistry, amino acids, in particular, in collaboration with Professors P. Bravo (Milan, Italy, 1993), Yu. Belokon’ (Moscow, USSR, 1987-1990), T. Hayashi (Sapporo, Japan, 1994-1995), and V. Hruby (Tucson, USA, 1998-2000). Since 2001, he is a Professor of chemistry at the University of Oklahoma. He is a Member of the international advisory Editorial Board of Journal of Fluorine Chemistry (2003-present), Journal of Amino Acids (2008-present), Vice Chair /Membership and Chair Elect of the ACS Fluorine Division, author of 160+ research papers, 10 book-chapters, 9 patents, Editor of 6 books and 5 Special Issues of Tetrahedron (2), Tetrahedron: Asymmetry (1), and Journal of Fluorine Chemistry (2). His current h and m indexes are 30 and 1.4, respectively. He has a wide range of research interests, which include (1) general asymmetric synthesis of alpha-amino acids; (2) organocatalytic reducing processes via biomimetic 1,3-proton shift reaction; (3) self-disproportionation of enantiomers as a general mechanism of chiral “annihilation” leading to formation of pre-biotic homo-chirality; (5) design and synthesis of molecules with switchable chirality via formation and cleavage of metal-ligand coordination bonds; (7) development of novel proline-alpha-amino acid chimera scan, as a methodologically new approach for investigation of peptides bioactive conformations and secondary/tertiary structures; (9) design, synthesis and bioactivity studies of novel bi- and trivalent peptidomimetics and beta turns.
Biography Updated on 2 December 2010