Helmut Butzkueven

Howard Florey Institute, Australia

Helmut Butzkueven is a multiple sclerosis neurologist at the Royal Melbourne Hospital and the Director of MS services at Box Hill Hospital. He is a Senior Research Fellow at the Florey Institute and an Honorary Associate Professor at the Centre for Neuroscience, University of Melbourne. His basic science research interest is the characterization of molecular and cellular CNS responses to autoimmune injury in animal models of MS. He leads a number of human studies, particularly focusing on large-scale MS epidemiology, development of new biomarkers for axonal degeneration in MS, and understanding the effects of MS risk genes. Two of his papers have produced seminal contributions in top-ranked general scientific journals, namely, “LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival” (Nature Medicine, 2002) and “The ANZGENE consortium Genome-wide association scan identifies novel multiple sclerosis susceptibility loci on chromosomes 12 and 20” (Nature Genetics, 2009). Butzkueven is the recipient of 8 research prizes and awards including the 1998 St Vincent’s Hospital Novartis Medal for Clinical Research, the 2002 Royal Melbourne Hospital Cleveland Prize for Medical Research, the 2004 Bethlehem Griffith Award for Medical Research, and the 2009 Eureka Prize for Medical Research (as part of the MS Group, Howard Florey Institute). Since 2005, he has been the Chief Investigator of the international MS basis study (MS incident cohort study) (50 MS centres, 22 countries, 2110 patients) and, since 2004, the Chairman of the MS Base Foundation (http://www.msbase.org) providing a seminal contribution to this global online MS database with 11 950 patients (54 centers, 27 countries). Dr. Butzkueven is currently supervising 5 postgraduate students, 1 postdoctoral fellow, 2 research assistants, and 2 research nurses.

Biography Updated on 15 November 2009

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