Joseph J. McArdle

University of Medicine and Dentistry of New Jersey, USA

Joseph J. McArdle New Jersey Medical School, Newark, USA Joseph J. McArdle was born in Wilmington, Delaware in 1945. He earned a BA in Biology and Chemistry from the University of Delaware (1967) and a PhD in Cellular Neuropharmacology from the State University of New York at Buffalo (1972) with Edson X. Albuquerque. While a lieutenant in the US Army reserve from 1967 to 1975, he joined the faculty of the NJ Medical School where he is currently Professor of Pharmacology and Physiology. The focus of his research is the neuromuscular junction (NMJ). Specifically, NMJ development and recovery from peripheral nerve damage. This research utilizes toxins, drugs, as well as genetically altered mice to explore the molecular processes involved in NMJ plasticity and trophic regulation of muscle. He has studied the NMJ with Alberto Mallart and Peter Gage at the CNRS, Gif-sur-Yvette, France (1979) and the John Curtin School of Medical Research, Canberra, Australia (1987), respectively. After learning neuronal tissue culture in the laboratory of Phillip Nelson (Developmental Neurobiology, NICHHD, Bethesda, USA, 1987), he studied the action of drugs of abuse on voltage and ligand gated ion channels using patch clamp techniques. His laboratory applied these techniques to the study of myocardial calcium channels in a rat model of hypertension. He has served as an ad hoc and full time reviewer of research applications to the National Science Foundation and the National Institutes of Health. Biography Updated on 8 January 2009

Biography Updated on 11 January 2009

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