Chandra Prakash

Agios Pharmaceuticals, USA


Chandra Prakash is a Senior Director in the Department of Drug Metabolism and Preclinical Safety, Biogen Idec, Cambridge, Mass, USA. He obtained his Ph.D. degree in organic chemistry in 1977. He held several academic appointments the last of which serving as a Research Associate Professor and as an Associate Director of mass spectrometry resources at the Vanderbilt University, Nashville, Tenn, USA. In 1992, he joined Pfizer Global Research and Development as a Senior Research Investigator in the Department of Pharmacokinetics, Dynamics, and Metabolism (PDM) and promoted to Research Fellow (2004). He joined Biogen Idec in 2008. For the last 30 years, Dr. Prakash has been involved in the drug metabolism and clinical PK studies to support drug discovery, development, and registration. His research interests include application of LC-MS and radio detection techniques, development of chemical model to mimic CYP metabolic activities, metabolic bioactivation, and reaction phenotyping of metabolizing enzymes to facilitate the discovery and development of new chemical entities as drug candidates. He is an author of more than 250 manuscripts, book chapters, abstracts, and patents. He reviews extensively for a number of scientific journals and serves as an Editor-in-Chief of the Journals “Current Drug Metabolism” and “Drug Metabolism Letters.” He is also on the editorial board of the journal “Expert Opinion on Drug Metabolism & Toxicology.“ Dr. Prakash is a Member of ASPET, ASMS, ISSX, and ASFP.

Biography Updated on 13 December 2012

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