Valerie Kouskoff

University of Manchester, United Kingdom

Valerie Kouskoff did her postgraduate training with Drs. Mathis and Benoist at Laboratoire de Genetique Moléculaire des Eucaryotes du CNRS, Strasbourg, France. Her Ph.D. degree study focused on understanding the molecular mechanisms involved in the thymic selection of T lymphocytes. During her postdoctoral training with Dr. Nemazee at the National Jewish Centre, Denver, CO, USA, she studied B lymphocyte-driven immune responses. Her next move led her to New York, USA, where she worked with Professor Keller at the Mount Sinai School of Medicine, NY, USA, on the development of the hematopoietic system. Since September 2003, Dr. Kouskoff has been a Group Leader at the CRUK Manchester Institute, Manchester, UK. The overarching goal of her research team is to further delineate and understand the transcriptional networks that orchestrate the formation of the hematopoietic system during embryonic development; many transcriptional regulators implicated in hematopoietic specification have been linked to leukemogenesis events, often as a result of aberrant expression. Through better understanding of the function of these transcriptional regulators at the onset of haematopoietic specification, they hope to gain insight into their potential role in the initiation and maintenance of haematological malignancies.

Biography Updated on 25 September 2014

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