Carol Feghali-Bostwick holds a Ph.D. degree. She is an Associate Professor at the Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, and Department of Pathology at the University of Pittsburgh, Pa, USA. She has a longstanding interest in systemic sclerosis (SSc) and fibrosis, and her research focuses on delineating the pathogenesis of fibrosis in skin and lung tissues of patients with SSc, idiopathic pulmonary fibrosis (IPF), and related conditions. Her research involves the examination of the role of environmental and genetic factors in the development of SSc in twins, the impact of epigenetic differences on disease discordance in twins, the role of insulin-like growth factor-binding proteins in the development of fibrosis, and the identification of diagnostic and prognostic markers such as the presence of antibodies to self-antigens in fibrotic diseases. More recently, Dr. Feghali-Bostwick has optimized use of a human skin organ culture model for assessing the effects of fibrotic and antifibrotic factors in human tissues and completed a gene expression profiling study that compared lung tissues and primary pulmonary fibroblasts from patients with SSc to patients with related lung diseases. She serves as a Vice Chair of the Board of Directors of the Scleroderma Foundation and chairs the Foundation’s Research Committee. She also codirects the Scleroderma Center at the University of Pittsburgh, mentors several physician scientists, serves on NIH study sections, and is a member of the editorial boards of three journals.
Biography Updated on 22 November 2011