Keith T. Ballingall

Moredun Research Institute, United Kingdom

Keith T. Ballingall graduated in immunology from the University of Strathclyde with a B.S. degree and in livestock molecular immunology from Edinburgh with a Ph.D. degree. His research interests are in the area of livestock-pathogen interactions at individual and population levels. His Ph.D. degree in molecular immunology with a focus on the genetic and diversity within the ovine MHC was followed by 5 years in Kenya working on the genetic control of the immune response to subunit vaccines against the protozoan parasite of cattle Theileria parva. On return to the UK, the mechanisms behind pathogen antigen processing and immune recognition formed the basis of a Wellcome Trust funded project investigating unique aspects of the ruminant major histocompatibility complex (MHC). This focused on ascribing molecular function to dendritic cell restricted immune response genes within the ruminant MHC. Since 2005, he has been involved in the generation; characterisation, and practical application of a unique sheep MHC defined resource flock at the Moredun Research Institute. This flock allows longer term and more detailed dissections of the mechanisms of protective immunity to sheep pathogens, the identification of the pathogen molecules involved and the subsequent development of vaccines based on these molecules. Since 2007, he has been closely involved in comparative aspects of MHC genetic diversity and currently chair the International Society for Animal Genetics/International Union of Immunological Societies/Veterinary Immunology Committee, Comparative MHC Nomenclature Committee.

Biography Updated on 13 April 2011

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