Barbara Picconi received the B.S. degree from Sapienza University of Rome, Rome, Italy, in 1995, and the Ph.D. degree in neuroscience from Tor Vergata University of Rome in 2004. In 1998–2000, she received the Telethon Foundation Grant Fellowship (Department of Neuroscience, Tor Vergata University of Rome, Professor Paolo Calabresi). Since 2005, Picconi has been a Researcher at the Laboratory of Neurophysiology, Santa Lucia Foundation, Rome, Italy. Since the beginning of her scientific career in neuroscience in the group of Professor Calabresi, Picconi has been involved in the electrophysiological characterization of corticostriatal synapses with particular interest on the role of DA in striatal functions by using in vitro preparation. Soon after, she started to focus her interest on behavioural and synaptic aspects of experimental models of Parkinson’s Disease, by lesioning the ascending nigrostriatal dopamine (DA) pathway with the 6-OHDA toxin that mimics parkinsonian pathology and, then, characterizing the synaptic plasticity changes in the corticostriatal pathway. Over the years of her Ph.D. degree training, Picconi started to study the alterations occurring in the corticostriatal synaptic transmission after DA denervation in this useful experimental model of PD. During her Ph.D. degree studies, she had the chance to spend few months at the Laboratory of Neurobiology, in Wallenberg Centre (Sweden) directed by Professor Cenci-Nilsson, who is an expert in a model of L-DOPA-induced dyskinesia in rodents.
Biography Updated on 9 September 2012