Frank S. Hall

The University of Toledo, USA


After receiving a B.A. degree in psychology from Harvard University in 1987, Frank Scott Hall pursued graduate work at Cambridge University with Professor Trevor W. Robbins, F.R.S. In 1994, Dr. Hall received a Ph.D. degree in neurobiology for his thesis entitled “The behavioral and neurochemical effects of social separation on the rat” which investigated the effects of early social deprivation on brain monoamine systems using behavioral, pharmacological, and neurochemical approaches. This thesis developed isolation-rearing as an animal model of schizophrenia that has greater validity than other models and subsequently has become widely used by pharmaceutical companies developing novel therapeutics. As a Postdoctoral Fellow, Dr. Hall was a National Research Council Research Associate at the National Institute on alcoholism and alcohol abuse, where he worked with the Scientific Director, Dr. Markku Linnoila. During his postgraduate work Dr. Hall pursued his interests in environmental effects on psychopathological phenotypes using animal models, incorporating genetic components to begin to study gene-environment interactions. With the ultimate goal of understanding the genetic underpinnings of gene-environment interactions in isolation-rearing, Dr. Hall joined the Molecular Neurobiology Branch at the National Institute on Drug Abuse in 1999. Dr. Hall led the transgenic mouse group from 2001 to 2014, investigating the molecular genetic basis of addiction and related psychiatric phenotypes. This work has characterized the polygenic basis of these phenotypes but is also the groundwork for future studies to examine the molecular basis of gene-environment interactions. Dr. Hall is currently an Assistant Professor of pharmacology at The University of Toledo College of Pharmacy and Pharmaceutical Sciences where his research investigates genetic and developmental influences on sensitivity to drugs of abuse. Dr. Hall has authored over 100 scientific articles.

Biography Updated on 26 May 2016

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